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Merck
CN

901763

PC biotin-azide

Synonym(s):

rel-1-[4-[[22-[(3aR,4R,6aS)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-4,18-dioxo-8,11,14-trioxa-5,17-diazadocos-1-yl]oxy]-5-methoxy-2-nitrophenyl]ethyl N-(3-azidopropyl)carbamate

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About This Item

Empirical Formula (Hill Notation):
C35H55N9O12S
CAS Number:
Molecular Weight:
825.93
UNSPSC Code:
12352125
NACRES:
NA.22
MDL number:
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form

powder or crystals

availability

available only in USA

storage temp.

−20°C

SMILES string

S1[C@H]([C@H]3NC(=O)N[C@H]3C1)CCCCC(=O)NCCOCCOCCOCCNC(=O)CCCOc2c(cc(c(c2)[N+](=O)[O-])C(OC(=O)NCCCN=[N+]=[N-])C)OC

InChI key

PTNZFIYMARMNDM-MJUSKHNJSA-N

Application

PC biotin-azide is an azide-activated photoclevable biotin probe that allows for reagent-free release of the captured biomolecules from streptavidin. This reagent contains a biotin moiety linked to an azide group through a spacer arm containing a photocleavable moiety. Captured biomolecules can be efficiently photoreleased, typically >90% in 5-25 minutes using an inexpensive, near-UV, low-intensity lamp (e.g. 365 nm lamp at 1-5 mW/cm2).


pictograms

Flame

signalword

Danger

hcodes

Hazard Classifications

Self-react. C

Storage Class

5.2 - Organic peroxides and self-reacting hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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