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901765

Dde biotin-azide

Synonym(s):

rel-(3aR,4R,6aS)-N-[19-Azido-15-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3,6,9,12-tetraoxa-16-azanonadec-1-yl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide

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About This Item

Empirical Formula (Hill Notation):
C32H53N7O8S
CAS Number:
1802907-93-2
Molecular Weight:
695.87
UNSPSC Code:
12352125
NACRES:
NA.22
MDL number:
MFCD28505550
Form:
liquid
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form

liquid

reaction suitability

reaction type: click chemistry

storage temp.

−20°C (−15°C to −25°C)

SMILES string

S1[C@H]([C@H]3NC(=O)N[C@H]3C1)CCCCC(=O)NCCOCCOCCOCCOCCC(=C2C(=O)CC(CC2=O)(C)C)NCCCN=[N+]=[N-]

InChI

1S/C32H53N7O8S/c1-32(2)20-25(40)29(26(41)21-32)23(34-9-5-10-36-39-33)8-12-44-14-16-46-18-19-47-17-15-45-13-11-35-28(42)7-4-3-6-27-30-24(22-48-27)37-31(43)38-30/h24,27,30,34H,3-22H2,1-2H3,(H,35,42)(H2,37,38,43)/t24-,27-,30-/m0/s1

InChI key

HUAWNOKWZYCBQA-LFERIPGTSA-N

Application

Extraordinary strength of the streptavidin-biotin interaction allows for efficient capturing of even highly dilute targets; however, it makes recovery of proteins from affinity resins challenging. This reagent contains a biotin moiety linked to an azide moiety through a spacer arm containing a hydrazine-cleavable Dde linker. Typically >90% of captured biomolecules can be efficiently released.

Storage Class

10 - Combustible liquids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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