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Merck
CN

901767

PC biotin-PEG3-NHS ester

Synonym(s):

PC biotin-NHS ester

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About This Item

Empirical Formula (Hill Notation):
C36H52N6O15S
CAS Number:
2353409-93-3
Molecular Weight:
840.89
MDL number:
MFCD31811520
UNSPSC Code:
51171641
NACRES:
NA.22

Key Documents

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InChI

1S/C36H52N6O15S/c1-23(56-36(48)57-41-32(45)9-10-33(41)46)24-20-27(51-2)28(21-26(24)42(49)50)55-13-5-8-31(44)38-12-15-53-17-19-54-18-16-52-14-11-37-30(43)7-4-3-6-29-34-25(22-58-29)39-35(47)40-34/h20-21,23,25,29,34H,3-19,22H2,1-2H3,(H,37,43)(H,38,44)(H2,39,

InChI key

WXAMRLAFOFNACR-VTJXTUSFSA-N

SMILES string

S1[C@H]([C@H]4NC(=O)N[C@H]4C1)CCCCC(=O)NCCOCCOCCOCCNC(=O)CCCOc2c(cc(c(c2)[N+](=O)[O-])C(OC(=O)ON3C(=O)CCC3=O)C)OC

form

solid

reaction suitability

reaction type: click chemistry
reagent type: cross-linking reagent

mp

170 °C

storage temp.

−20°C

Related Categories

Application

PC biotin-NHS ester is a unique amine-reactive, photocleavable biotin reagent that allows for reagent-free release of the captured biomolecules from streptavidin. This reagent contains a biotin moiety linked to the amine reactive N-hydroxysuccinimidyl (NHS) mixed carbonate through a spacer arm containing a photocleavable moiety. The NHS portion of this compound reacts specifically with primary amine groups on the target molecule(s) to form a carbamate linkage. Captured biomolecules can be efficiently photoreleased, typically >90% in 5-25 minutes using an inexpensive, near-UV, low intensity lamp (e.g. 365 nm lamp at 1-5 mW/cm2).

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKCW6727
MKCV8589
MKCS5656
MKCQ1420
MKCL9445

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Articles

Crosslinkers Selection Guide

Choosing the right crosslinker for your biochemical or bioconjugation research can be challenging. Our selection guide can help you find the perfect match for your applications.

交联剂选择指南

为您的生化或生物共轭研究选择合适的交联剂可能具有挑战性。我们的选择指南可以帮助您找到最适合您应用的交联剂。

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