90240
Glyceryl triacetate
≥99.0% (GC)
Synonym(s):
1,2,3-Triacetoxypropane, 1,2,3-Triacetylglycerol, Glycerol triacetate, Triacetin
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About This Item
Linear Formula:
(CH3COOCH2)2CHOCOCH3
CAS Number:
Molecular Weight:
218.20
UNSPSC Code:
12352211
NACRES:
NA.25
PubChem Substance ID:
EC Number:
203-051-9
Beilstein/REAXYS Number:
1792353
MDL number:
Product Name
Glyceryl triacetate, ≥99.0% (GC)
InChI key
URAYPUMNDPQOKB-UHFFFAOYSA-N
InChI
1S/C9H14O6/c1-6(10)13-4-9(15-8(3)12)5-14-7(2)11/h9H,4-5H2,1-3H3
SMILES string
CC(=O)OCC(COC(C)=O)OC(C)=O
assay
≥99.0% (GC)
form
liquid
Quality Level
greener alternative product characteristics
Less Hazardous Chemical Syntheses
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
refractive index
n20/D 1.431
bp
258-260 °C (lit.)
density
1.158 g/mL at 20 °C
greener alternative category
lipid type
saturated FAs
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Application
- Epigenetic priming targets tumor heterogeneity to shift transcriptomic phenotype of pancreatic ductal adenocarcinoma towards a Vitamin D susceptible state.: This groundbreaking study utilizes glyceryl triacetate as part of an epigenetic priming strategy to sensitize pancreatic ductal adenocarcinoma to Vitamin D, marking a significant advancement in cancer treatment modalities (He et al., 2024).
- Glyceryl triacetate promotes blood-brain barrier recovery after ischemic stroke through lipogenesis-mediated IL-33 in mice.: Research demonstrates glyceryl triacetate′s effectiveness in enhancing blood-brain barrier repair post-ischemic stroke via lipogenesis pathways, offering insights into novel stroke recovery treatments (Wei et al., 2023).
- Development of A Nanostructured Lipid Carrier-Based Drug Delivery Strategy for Apigenin: Experimental Design Based on CCD-RSM and Evaluation against NSCLC In Vitro.: This study details the formulation of a nanostructured lipid carrier incorporating glyceryl triacetate, optimized for delivering apigenin to combat non-small cell lung cancer, emphasizing the potential of glyceryl triacetate in targeted therapy applications (Wang et al., 2023).
- Are New Phthalate Ester Substitutes Safer than Traditional DBP and DiBP Comparative Endocrine-Disrupting Analyses on Zebrafish Using In Vivo, Transcriptome, and In Silico Approaches.: Investigating glyceryl triacetate as a safer alternative to traditional phthalate esters, this study explores its lower endocrine-disrupting effects, contributing to safer industrial and pharmaceutical applications (Tan et al., 2023).
- Glyceryl triacetate feeding in mice increases plasma acetate levels but has no anticonvulsant effects in acute electrical seizure models.: This research evaluates the biochemical impact of glyceryl triacetate on plasma acetate levels, providing valuable data on its metabolic effects despite a lack of anticonvulsant properties in specific seizure models (Xu et al., 2022).
General description
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product can replace highly toxic diluents in membrane preparation and thus aligns with "Less Hazardous Chemical Syntheses". Click here for more information.
Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
298.4 °F - closed cup
flash_point_c
148 °C - closed cup
ppe
Eyeshields, Gloves
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Huayin Pu et al.
Journal of agricultural and food chemistry, 59(10), 5738-5745 (2011-04-26)
An oral colon-targeting controlled release system based on resistant starch acetate (RSA) as a film-coating material was developed. The RSA was successfully synthesized, and its digestion resistibility could be improved by increasing the degree of substitution (DS), which was favorable
Hui Liu et al.
Journal of pharmaceutical sciences, 101(5), 1783-1793 (2012-02-10)
Although injectable depot-forming solutions have been commercialized, the factors that influence the overall release kinetics from such systems are still not fully understood. In this work, we address the effect of cosolvent on the issue of excessive burst release of
Reeval Segel et al.
Molecular genetics and metabolism, 103(3), 203-206 (2011-04-09)
Canavan disease (CD MIM#271900) is a rare autosomal recessive neurodegenerative disorder presenting in early infancy. The course of the disease is variable, but it is always fatal. CD is caused by mutations in the ASPA gene, which codes for the
Seung Jun Choi et al.
Journal of agricultural and food chemistry, 57(23), 11349-11353 (2009-11-07)
Citral is widely used in the beverage, food, and fragrance industries for its characteristic flavor profile. However, it chemically degrades over time in aqueous solutions due to an acid-catalyzed reaction, which leads to loss of desirable flavor notes and formation
Peethambaran Arun et al.
Journal of neurotrauma, 27(1), 293-298 (2009-10-07)
Patients suffering from traumatic brain injury (TBI) have decreased markers of energy metabolism, including N-acetylaspartate (NAA) and ATP. In the nervous system, NAA-derived acetate provides acetyl-CoA required for myelin lipid synthesis. Acetate can also be oxidized in mitochondria for the
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