Merck
CN
All Photos(2)

90323

Supelco

Clofibric acid

analytical standard

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Synonym(s):
2-(p-Chlorophenoxy)-2-methylpropionic acid, α-(p-Chlorophenoxy)isobutyric acid, Clofibric acid
Linear Formula:
ClC6H4OC(CH3)2CO2H
CAS Number:
Molecular Weight:
214.65
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

Assay

≥99.0% (GC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

impurities

≤0.5% water

mp

120-122 °C (lit.)

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CC(C)(Oc1ccc(Cl)cc1)C(O)=O

InChI

1S/C10H11ClO3/c1-10(2,9(12)13)14-8-5-3-7(11)4-6-8/h3-6H,1-2H3,(H,12,13)

InChI key

TXCGAZHTZHNUAI-UHFFFAOYSA-N

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This Item
1977774132690568
Clofibric acid analytical standard

Supelco

90323

Clofibric acid

Clofibrate analytical standard

Supelco

41326

Clofibrate

Fenofibric acid analytical standard

Supelco

90568

Fenofibric acid

assay

≥99.0% (GC)

assay

97%

assay

≥99.0% (GC)

assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

limited shelf life, expiry date on the label

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

application(s)

-

application(s)

forensics and toxicology
pharmaceutical (small molecule)

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

format

-

format

neat

format

neat

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Agustina Manassero et al.
Environmental science and pollution research international, 22(2), 926-937 (2014-03-14)
A kinetic study of the photocatalytic degradation of the pharmaceutical clofibric acid is presented. Experiments were carried out under UV radiation employing titanium dioxide in water suspension. The main reaction intermediates were identified and quantified. Intrinsic expressions to represent the
Da-Bing Ren et al.
Journal of chromatography. A, 1355, 80-85 (2014-06-22)
Selection of an appropriate solvent system is of great importance for a successful counter-current chromatography separation. In this work, the nonrandom two-liquid (NRTL) model, a thermodynamic method, was used for predicting the partition coefficient based on a few measured partition
Zein Shaban Ibrahim et al.
Bioscience, biotechnology, and biochemistry, 78(9), 1550-1559 (2014-07-24)
Peroxisome proliferator activated receptor α (PPARα) ligands, fibrates used to control hyperlipidemia. We demonstrated CYP2B induction by clofibric acid (CFA) however, the mechanism was not clear. In this study, HepG2 cells transfected with expression plasmid of mouse constitutive androstane receptor
Martin J A Schackmann et al.
Biochimica et biophysica acta, 1851(2), 231-237 (2014-12-17)
X-linked adrenoleukodystrophy (X-ALD) is a neurometabolic disease that is caused by mutations in the ABCD1 gene. ABCD1 protein deficiency impairs peroxisomal very long-chain fatty acid (VLCFA) degradation resulting in increased cytosolic VLCFA-CoA levels, which are further elongated by the VLCFA-specific
Julia Martín et al.
The Science of the total environment, 503-504, 97-104 (2014-06-10)
Sewage sludge disposal onto lands has been stabilized previously but still many pollutants are not efficiently removed. Special interest has been focused on pharmaceutical compounds due to their potential ecotoxicological effects. Nowadays, there is scarce information about their occurrence in

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