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Merck
CN

90899

Cannabidiol solution

~10 mg/mL in ethanol, analytical standard, for drug analysis

Synonym(s):

CBD

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About This Item

Empirical Formula (Hill Notation):
C21H30O2
CAS Number:
Molecular Weight:
314.46
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
200-578-6
MDL number:
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InChI key

QHMBSVQNZZTUGM-ZWKOTPCHSA-N

InChI

1S/C21H30O2/c1-5-6-7-8-16-12-19(22)21(20(23)13-16)18-11-15(4)9-10-17(18)14(2)3/h11-13,17-18,22-23H,2,5-10H2,1,3-4H3/t17-,18+/m0/s1

SMILES string

CCCCCc1cc(O)c([C@@H]2C=C(C)CC[C@H]2C(C)=C)c(O)c1

assay

≥98.5% (HPLC)

shelf life

limited shelf life, expiry date on the label

drug control

USDEA Schedule I; regulated under CDSA - not available from Sigma-Aldrich Canada

concentration

~10 mg/mL in ethanol

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

suitability

corresponds for H-NMR

application(s)

pharmaceutical (small molecule)

format

single component solution

storage temp.

2-8°C

Quality Level

Gene Information

human ... CNR1(1268)

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General description

Cannabidiol solution may be used for studies regarding the application of cannabidiol for immune-related diseases via studying its immunosuppressive mechanism.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

ampoule contains 1.2mL solution

pictograms

FlameExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

57.2 °F - closed cup

flash_point_c

14 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

监管及禁止进口产品
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Bruno Gavinho et al.
Frontiers in cellular and infection microbiology, 10, 417-417 (2020-10-20)
Giardia intestinalis is a microaerophilic protozoan that is an important etiologic agent of diarrhea worldwide. There is evidence that under diverse conditions, the parasite is capable of shedding extracellular vesicles (EVs) which modulate the physiopathology of giardiasis. Here we describe
Cannabidiol (CBD) induces functional Tregs in response to low-level T cell activation
Dhital S, et al.
Cellular Immunology, 312, 25-34 (2017)
Alline Cristina Campos et al.
Psychopharmacology, 226(1), 13-24 (2012-09-26)
Cannabidiol (CBD) is a non-psychotomimetic constituent of Cannabis sativa plant that promotes antianxiety and anti-panic effects in animal models after acute systemic or intra-dorsal periaqueductal gray (DPAG) administration. However, the effects of CBD repeated administration, and the possible mechanisms involved
R G Pertwee
British journal of pharmacology, 153(2), 199-215 (2007-09-11)
Cannabis sativa is the source of a unique set of compounds known collectively as plant cannabinoids or phytocannabinoids. This review focuses on the manner with which three of these compounds, (-)-trans-delta9-tetrahydrocannabinol (delta9-THC), (-)-cannabidiol (CBD) and (-)-trans-delta9-tetrahydrocannabivarin (delta9-THCV), interact with cannabinoid
Massimo Nabissi et al.
Carcinogenesis, 34(1), 48-57 (2012-10-20)
The aggressive behavior of Glioblastoma multiforme (GBM) is mainly due to high invasiveness and proliferation rate as well as to high resistance to standard chemotherapy. Several chemotherapeutic agents like temozolomide (TMZ), carmustine (BCNU) or doxorubicin (DOXO) have been employed for

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