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90899

Cannabidiol solution

Name: Cannabidiol solution
Brand: SIAL

~10 mg/mL in ethanol, analytical standard, for drug analysis

Synonym(s):

CBD

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About This Item

Empirical Formula (Hill Notation):

C₂₁H₃₀O₂

CAS Number:

13956-29-1

Molecular Weight:

314.46

NACRES:

NA.24

PubChem Substance ID:

329769963

UNSPSC Code:

41116107

EC Number:

200-578-6

MDL number:

MFCD00869597

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Quality Level

100

assay

≥98.5% (HPLC)

shelf life

limited shelf life, expiry date on the label

drug control

USDEA Schedule I; regulated under CDSA - not available from Sigma-Aldrich Canada

concentration

~10 mg/mL in ethanol

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

suitability

corresponds for H-NMR

application(s)

pharmaceutical (small molecule)

format

single component solution

storage temp.

2-8°C

SMILES string

CCCCCc1cc(O)c([C@@H]2C=C(C)CC[C@H]2C(C)=C)c(O)c1

InChI

1S/C21H30O2/c1-5-6-7-8-16-12-19(22)21(20(23)13-16)18-11-15(4)9-10-17(18)14(2)3/h11-13,17-18,22-23H,2,5-10H2,1,3-4H3/t17-,18+/m0/s1

InChI key

QHMBSVQNZZTUGM-ZWKOTPCHSA-N

Gene Information

human ... CNR1(1268)

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General description

Cannabidiol solution may be used for studies regarding the application of cannabidiol for immune-related diseases via studying its immunosuppressive mechanism.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

ampoule contains 1.2mL solution

pictograms

GHS02,GHS07

signalword

Danger

hcodes

H225,H319

pcodes

P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

57.2 °F - closed cup

flash_point_c

14 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

监管及禁止进口产品

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Certificates of Analysis (COA)

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Peptidylarginine Deiminase Inhibition Abolishes the Production of Large Extracellular Vesicles From Giardia intestinalis, Affecting Host-Pathogen Interactions by Hindering Adhesion to Host Cells.

Bruno Gavinho et al.

Frontiers in cellular and infection microbiology, 10, 417-417 (2020-10-20)

Giardia intestinalis is a microaerophilic protozoan that is an important etiologic agent of diarrhea worldwide. There is evidence that under diverse conditions, the parasite is capable of shedding extracellular vesicles (EVs) which modulate the physiopathology of giardiasis. Here we describe

Cannabidiol (CBD) induces functional Tregs in response to low-level T cell activation

Dhital S, et al.

Cellular Immunology, 312, 25-34 (2017)

A critical review of the antipsychotic effects of cannabidiol: 30 years of a translational investigation.

Antonio Waldo Zuardi et al.

Current pharmaceutical design, 18(32), 5131-5140 (2012-06-22)

Δ(9)-tetrahydrocannabinol (Δ(9)-THC) is the main compound of the Cannabis Sativa responsible for most of the effects of the plant. Another major constituent is cannabidiol (CBD), formerly regarded to be devoid of pharmacological activity. However, laboratory rodents and human studies have

Cannabidiol: from an inactive cannabinoid to a drug with wide spectrum of action.

Antonio Waldo Zuardi

Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999), 30(3), 271-280 (2008-10-04)

The aim of this review is to describe the historical development of research on cannabidiol. This review was carried out on reports drawn from Medline, Web of Science and SciELO. After the elucidation of the chemical structure of cannabidiol in

Involvement of serotonin-mediated neurotransmission in the dorsal periaqueductal gray matter on cannabidiol chronic effects in panic-like responses in rats.

Alline Cristina Campos et al.

Psychopharmacology, 226(1), 13-24 (2012-09-26)

Cannabidiol (CBD) is a non-psychotomimetic constituent of Cannabis sativa plant that promotes antianxiety and anti-panic effects in animal models after acute systemic or intra-dorsal periaqueductal gray (DPAG) administration. However, the effects of CBD repeated administration, and the possible mechanisms involved

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Global Trade Item Number

SKU	GTIN
90899-1ML	04061838089649

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