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91209

Carnosic acid

analytical standard

Synonym(s):

(4aR,10aS)-5,6-Dihydroxy-7-isopropyl-1,1-dimethyl-1,3,4,9,10,10a-hexahydro-2H-phenanthrene-4a-carboxylic acid, Salvin

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About This Item

Empirical Formula (Hill Notation):
C20H28O4
CAS Number:
3650-09-7
Molecular Weight:
332.43
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
329770003
MDL number:
MFCD02259459
Beilstein/REAXYS Number:
2707918
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grade

analytical standard

Quality Level

100

assay

≥95.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

impurities

≤5.0% water

application(s)

food and beverages

format

neat

storage temp.

−20°C

SMILES string

CC(C)c1cc2CC[C@H]3C(C)(C)CCC[C@]3(C(O)=O)c2c(O)c1O

InChI

1S/C20H28O4/c1-11(2)13-10-12-6-7-14-19(3,4)8-5-9-20(14,18(23)24)15(12)17(22)16(13)21/h10-11,14,21-22H,5-9H2,1-4H3,(H,23,24)/t14-,20+/m0/s1

InChI key

QRYRORQUOLYVBU-VBKZILBWSA-N

General description

Carnosic acid is a polyphenolic diterpene, which can be obtained from rosemary. It may possess various pharmacological properties like antioxidant, anticancer and also antimutagenic property.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCJ6845
BCCJ0627
BCCH9050
BCCH6821
BCCH4722

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Carnosic acid inhibits proliferation and augments differentiation of human leukemic cells induced by 1, 25-dihydroxyvitamin dsub3 and retinoic acid
Steiner M, et al.
Nutrition and Cancer, 41, 135-144 (2001)
Michael Danilenko et al.
Experimental cell research, 298(2), 339-358 (2004-07-22)
Differentiation therapy holds promise as an alternative to cytotoxic drug therapy of cancer. Among compounds under scrutiny for this purpose is the physiologically active form of vitamin D(3), 1,25-dihydroxyvitamin D(3), and its chemically modified derivatives. However, the propensity of vitamin
Ashley L Lennox et al.
Neuron, 106(3), 404-420 (2020-03-07)
De novo germline mutations in the RNA helicase DDX3X account for 1%-3% of unexplained intellectual disability (ID) cases in females and are associated with autism, brain malformations, and epilepsy. Yet, the developmental and molecular mechanisms by which DDX3X mutations impair
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Global Trade Item Number

SKUGTIN
91209-5MG04061833262351