916889
tert-Butyl 4-(4-(2-aminoethyl)phenyl)piperidine-1-carboxylate
≥95%
Synonym(s):
Semi-flexible linker for PROTAC® development
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Empirical Formula (Hill Notation):
C18H28N2O2
CAS Number:
Molecular Weight:
304.43
UNSPSC Code:
12352116
Product Name
tert-Butyl 4-(4-(2-aminoethyl)phenyl)piperidine-1-carboxylate, ≥95%
SMILES string
O=C(N(CC1)CCC1C(C=C2)=CC=C2CCN)OC(C)(C)C
assay
≥95%
form
powder
reaction suitability
reagent type: linker
functional group
Boc
amine
storage temp.
2-8°C
Quality Level
Application
tert-Butyl 4-(4-(2-aminoethyl)phenyl)piperidine-1-carboxylate is a 4-aryl piperidine useful as a semi-flexible linker in PROTAC development for targeted protein degradation. Incorporation of rigidity into the linker region of bifunctional protein degraders may impact the 3D orientation of the degrader and thus ternary complex formation as well as optimization of drug-like properties.
Other Notes
Legal Information
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service