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92264

4-Methoxyphenol

analytical standard

Synonym(s):

4-Hydroxyanisole, 4-MP, HQMME, Hydroquinone monomethyl ether, MEHQ, p-Guaiacol

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About This Item

Linear Formula:
CH3OC6H4OH
CAS Number:
150-76-5
Molecular Weight:
124.14
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
329769881
EC Number:
205-769-8
Beilstein/REAXYS Number:
507924
MDL number:
MFCD00002332
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grade

analytical standard

Quality Level

100

vapor density

4.3 (vs air)

vapor pressure

<0.01 mmHg ( 20 °C)

assay

≥98.5% (GC)

autoignition temp.

789 °F

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

impurities

≤0.5% water

bp

243 °C (lit.)

mp

55-57 °C (lit.)

application(s)

cleaning products
cosmetics
environmental
flavors and fragrances
food and beverages
personal care

format

neat

SMILES string

COc1ccc(O)cc1

InChI

1S/C7H8O2/c1-9-7-4-2-6(8)3-5-7/h2-5,8H,1H3

InChI key

NWVVVBRKAWDGAB-UHFFFAOYSA-N

Gene Information

human ... TYR(7299)

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General description

4-Methoxyphenol belongs to the class of hydroquinone (HQ) derivatives. It is widely used as a skin whitening agent, because it can exert hypo-pigmenting effects. It also finds applications as a stabilizer for chlorinated hydrocarbons, ethyl cellulose, UV (ultraviolet) inhibitor, inhibitor for acrylic monomers, etc.

Application

4-Methoxyphenol may be used as an analytical reference standard for the quantification of the analyte in cosmetic products using chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCP5447
BCCK8986
BCCG8757
BCCC0117
BCBX5348

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Proctor and Hughes' Chemical Hazards of the Workplace, 50(5-6), 346-352 (2004)
Experimental and statistical validation of HPLC analysis of hydroquinone and its 4-methoxyphenol, 4-ethoxyphenol and 4-benzyloxyphenol ethers in cosmetic products
Borremans M, et al.
Chromatographia, 50(5-6), 346-352 (1999)
Quantitative determination of $\alpha$-arbutin, $\beta$-arbutin, kojic acid, nicotinamide, hydroquinone, resorcinol, 4-methoxyphenol, 4-ethoxyphenol, and ascorbic acid from skin whitening products by HPLC-UV
Wang YH, et al.
Journal of AOAC (Association of Official Analytical Chemists) International, 98(1), 5-12 (2015)
Travis M Doggett et al.
Alcoholism, clinical and experimental research, 38(9), 2414-2426 (2014-09-27)
Alcohol intoxication can increase inflammation and worsen injury, yet the mechanisms involved are not clear. We investigated whether acute alcohol intoxication increases microvascular permeability and investigated potential signaling mechanisms in endothelial cells that may be involved. Conscious rats received a
Michael C Hill et al.
Advanced healthcare materials, 4(5), 714-722 (2014-12-23)
The extracellular environment exposes cells to numerous biochemical and physical signals that regulate their behavior. Strategies for generating continuous gradients of signals in biomaterials may allow for spatial control and patterning of cell behavior, and ultimately aid in the engineering
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Global Trade Item Number

SKUGTIN
92264-250MG04061833269251

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