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Glycine

analytical standard, for nitrogen determination according to Kjeldahl method

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Synonym(s):
2-Aminoacetic acid, Aminoacetic acid, Aminoethanoic acid, Glycocoll
Linear Formula:
NH2CH2COOH
CAS Number:
56-40-6
Molecular Weight:
75.07
Beilstein:
635782
EC Number:
200-272-2
MDL number:
MFCD00008131
eCl@ss:
32160406
PubChem Substance ID:
329770301
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥99.0%

analyte chemical class(es)

amino acids, peptides, proteins

technique(s)

HPLC: suitable
gas chromatography (GC): suitable
titration: suitable

impurities

18.6%±0.2% total nitrogen acc. to Kjeldahl

loss

≤0.05% loss on drying

pKa (25 °C)

(1) 2.35, (2) 9.60
2.35

mp

240 °C (dec.) (lit.)

solubility

1 M HCl: 75 mg/L, clear, colorless (2.252g in 30mL)

anion traces

chloride (Cl-): ≤50 mg/kg

cation traces

NH4+: ≤200 mg/kg

application(s)

food and beverages

format

neat

SMILES string

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

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General description

The glycine standard is produced under stringent conditions and measured with the highest possible precision.

Application

It can be used as an analytical standard to:
  • Evaluate Kjeldahl′s procedure to determine total protein content of reference standards used in clinical laboratories.
  • Analyze beer and wine for their protein and total usable nitrogen using a microwell ninhydrin assay.
  • Compare Kjeldahl and Dumas methods for routine analysis of dairy products in an interlaboratory study.
  • Simultaneously determine total phosphorus and total Kjeldahl nitrogen in surface water samples.
  • Quantitatively determine nitrate in surface waters using Valdetrama method.
  • Measure low level Kjeldahl nitrogen using an AutoAnalyzer.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Features and Benefits

  • Available in a neat format in a secure glass bottle to ensure its stability for the entire shelf life until opened.
  • High-quality offering accurate titer determinations

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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The Structure of Glycine Dihydrate: Implications for the Crystallization of Glycine from Solution and Its Structure in Outer Space
Xu W, et al.
Angewandte Chemie (Weinheim an der Bergstrasse, Germany), 129, 2062-2066 (2017)
Structure of Glycine Dihyrate: Its Implications to Crystallization of Glycine from Solution and Modification of Glycine in Space
Hu.T.C, et al.
Acta Crystallographica Section A, Foundations of Crystallography, 73 (2017)
Alexander Carvajal-González et al.
Brain : a journal of neurology, 137(Pt 8), 2178-2192 (2014-06-22)
The clinical associations of glycine receptor antibodies have not yet been described fully. We identified prospectively 52 antibody-positive patients and collated their clinical features, investigations and immunotherapy responses. Serum glycine receptor antibody endpoint titres ranged from 1:20 to 1:60 000.
Zoé Husson et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(28), 9418-9431 (2014-07-11)
The principal neurons of the cerebellar nuclei (CN), the sole output of the olivo-cerebellar system, receive a massive inhibitory input from Purkinje cells (PCs) of the cerebellar cortex. Morphological evidence suggests that CN principal cells are also contacted by inhibitory
Li-Chun Tu et al.
The EMBO journal, 32(24), 3220-3230 (2013-11-12)
Nuclear pore complexes (NPCs) mediate cargo traffic between the nucleus and the cytoplasm of eukaryotic cells. Nuclear transport receptors (NTRs) carry cargos through NPCs by transiently binding to phenylalanine-glycine (FG) repeats on intrinsically disordered polypeptides decorating the NPCs. Major impediments
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