94145
7α-Hydroxy-4-cholesten-3-one-25,26,26,26,27,27,27-d7
≥95.0% (HPLC)
Synonym(s):
7α-Hydroxycholest-4-en-3-one-d7
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About This Item
Empirical Formula (Hill Notation):
C27D7H37O2
Molecular Weight:
407.68
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24
grade
analytical standard
Quality Level
assay
≥95.0% (HPLC)
application(s)
clinical testing
format
neat
storage temp.
−20°C
SMILES string
O=C1CC[C@@]2(C)C(C[C@@H](O)[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CCCC(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])=C1
InChI key
IOIZWEJGGCZDOL-CTNVFXSSSA-N
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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W Gordon Brydon et al.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 25(6), 319-323 (2011-07-19)
Bile acid malabsorption (BAM) is a recognized cause of watery diarrhea, often diagnosed empirically based on clinical response to cholestyramine. The radionuclide selenium-labelled homocholic acid-taurine whole body retention test is expensive, labour intensive and of limited availability. To report on
Akira Honda et al.
Journal of lipid research, 48(2), 458-464 (2006-11-10)
We describe a highly sensitive and specific method for the quantification of serum 7alpha-hydroxy-4-cholesten-3-one (C4), which has been used as a biomarker for bile acid biosynthesis. This method is based upon a stable isotope dilution technique by liquid chromatography-tandem mass
David W Russell
Annual review of biochemistry, 72, 137-174 (2003-01-25)
The synthesis and excretion of bile acids comprise the major pathway of cholesterol catabolism in mammals. Synthesis provides a direct means of converting cholesterol, which is both hydrophobic and insoluble, into a water-soluble and readily excreted molecule, the bile acid.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 94145-1MG | 04061826231449 |