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Merck
CN

94145

7α-Hydroxy-4-cholesten-3-one-25,26,26,26,27,27,27-d7

≥95.0% (HPLC)

Synonym(s):

7α-Hydroxycholest-4-en-3-one-d7

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About This Item

Empirical Formula (Hill Notation):
C27D7H37O2
Molecular Weight:
407.68
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24
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grade

analytical standard

Quality Level

assay

≥95.0% (HPLC)

application(s)

clinical testing

format

neat

storage temp.

−20°C

SMILES string

O=C1CC[C@@]2(C)C(C[C@@H](O)[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CCCC(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])=C1

InChI key

IOIZWEJGGCZDOL-CTNVFXSSSA-N



Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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W Gordon Brydon et al.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 25(6), 319-323 (2011-07-19)
Bile acid malabsorption (BAM) is a recognized cause of watery diarrhea, often diagnosed empirically based on clinical response to cholestyramine. The radionuclide selenium-labelled homocholic acid-taurine whole body retention test is expensive, labour intensive and of limited availability. To report on
Akira Honda et al.
Journal of lipid research, 48(2), 458-464 (2006-11-10)
We describe a highly sensitive and specific method for the quantification of serum 7alpha-hydroxy-4-cholesten-3-one (C4), which has been used as a biomarker for bile acid biosynthesis. This method is based upon a stable isotope dilution technique by liquid chromatography-tandem mass
Cecilia Gälman et al.
Gastroenterology, 129(5), 1445-1453 (2005-11-16)
The conversion of cholesterol to bile acids by the liver is an important regulator of body cholesterol homeostasis. In rodents, both cholesterol and bile acid synthesis have marked diurnal rhythms that peak synchronously at midnight. The aim of this study



Global Trade Item Number

SKUGTIN
94145-1MG04061826231449