Skip to Content
Merck
CN

94972

Brombuterol hydrochloride

VETRANAL®, analytical standard

Synonym(s):

1-(4-Amino-3,5-dibromophenyl)-2-tert-butylaminoethanol hydrochloride

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C12H18Br2N2O · HCl
CAS Number:
21912-49-2
Molecular Weight:
402.55
NACRES:
NA.24
PubChem Substance ID:
329770406
UNSPSC Code:
41116107
MDL number:
MFCD10567368

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Brombuterol hydrochloride, VETRANAL®, analytical standard

InChI

1S/C12H18Br2N2O.ClH/c1-12(2,3)16-6-10(17)7-4-8(13)11(15)9(14)5-7;/h4-5,10,16-17H,6,15H2,1-3H3;1H

SMILES string

Cl.CC(C)(C)NCC(O)c1cc(Br)c(N)c(Br)c1

InChI key

XGPFKIAOVSGRSY-UHFFFAOYSA-N

grade

analytical standard

product line

VETRANAL®

assay

≥99.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable
solid phase extraction (SPE): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

Quality Level

100

Related Categories

Application

Brombuterol hydrochloride may be used as an analytical reference standard for the quantification of the analyte in complex matrices and biological samples using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Brombuterol hydrochloride is a beta-sympathomimetic compound with tocolytic, muscle-relaxant and bronchodilator properties and is widely used in therapy for their growth promoting and performance enhancement.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCL1420
BCCH7200
BCCD6423
BCCC3625
BCBX4230

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

E Sangiorgi et al.
Journal of chromatography. B, Biomedical sciences and applications, 693(2), 468-478 (1997-06-06)
The multistep analytical procedure routinely applied in our laboratory for the detection of the aryl amine beta-agonists clenbuterol, mabuterol and mapenterol in bovine matrices has been extended to the analysis in urine samples of brombuterol, a new clenbuterol-like compound. In
Analysis of beta-agonist residues in bovine hair: Development of a UPLC?MS/MS method and stability study
Giannetti L, et al.
Journal of Chromatography. B, Biomedical Applications, 1036(3), 76-83 (2016)
Overcoming matrix effects in electrospray: Quantitation of ?-agonists in complex matrices by isotope dilution liquid chromatography?mass spectrometry using singly 13C-labeled analogues
Gonzalez-Antuna A, et al.
Journal of Chromatography A, 40-47 (2013)
C Montesissa et al.
Xenobiotica; the fate of foreign compounds in biological systems, 28(11), 1049-1060 (1999-01-08)
1. Clenbuterol (CBL) and bromobuterol (BBL) were both extensively metabolized by hepatic microsomes of swine to only one polar metabolite which was separated by hplc and purified to perform mass analysis. 2. LC-MIS analysis by direct infusion into an ion
Leslie C Dickson et al.
Journal of AOAC International, 88(1), 46-56 (2005-03-12)
A multiresidue method was developed and validated to screen bovine urine samples for 10 beta-2-adrenergic agonistic drugs--brombuterol, cimaterol, clenbuterol, clenpenterol, isoxsuprine, mabuterol, ractopamine, ritodrine, salbutamol, and tulobuterol--at the 2 microg/L level. The method is also quantitative in the range of
View All Related Papers

Articles

Determination of 11 Beta Agonist Residues in Pork by LC-MS

Using an Ascentis® Express F5 HPLC column, this study separates 11 β-agonists in pork by LC-MS/MS in under 8 minutes with excellent recovery and precision.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service