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Menthone

analytical standard

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Synonym(s):
2-Isopropyl-5-methylcyclohexanone
Empirical Formula (Hill Notation):
C10H18O
CAS Number:
10458-14-7
Molecular Weight:
154.25
Beilstein:
774527
EC Number:
233-944-9
MDL number:
MFCD00062998
PubChem Substance ID:
329770455
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥81% (GC)
≥97.0% (mixture of isomers, GC)

optical activity

[α]/D -7.0±5°, neat

shelf life

limited shelf life, expiry date on the label

concentration

≤19% (isomenthone, minor component, GC)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.449-1.451

bp

85-88 °C/12 mmHg (lit.)

density

0.896 g/mL at 20 °C (lit.)

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care

format

neat

SMILES string

CC(C)C1CCC(C)CC1=O

InChI

1S/C10H18O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-9H,4-6H2,1-3H3

InChI key

NFLGAXVYCFJBMK-UHFFFAOYSA-N

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General description

Menthone belongs to the group of terpenes, found in a variety of volatile oils including pennyroyal, peppermint, and geranium. It finds applications in perfume and flavor compositions. Menthone is reported as a characteristic marker for the consumption of peppermint liqueurs, herbal, and bitter liqueurs.

Application

Menthone may be used as an analytical reference standard for the quantification of the analyte in food, pharmaceutical products, serum samples and Menthae Herba using chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Exclamation markHealth hazard
GHS07,GHS08

Signal Word

Danger

Hazard Statements

H302 - H319 - H334 - H412

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Resp. Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

156.2 °F - closed cup

Flash Point(C)

69 °C - closed cup

Certificates of Analysis (COA)

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Headspace solid-phase microextraction--gas chromatography--mass spectrometry determination of the characteristic flavourings menthone, isomenthone, neomenthol and menthol in serum samples with and without enzymatic cleavage to validate post-offence alcohol drinking claims
Schulz K, et al.
Analytica Chimica Acta, 646(1-2), 128-140 (2009)
Determination of menthol and menthone in food and pharmaceutical products by solid-phase microextraction--gas chromatography
Ligor M and Buszewski B
Journal of Chromatography A, 847(1-2), 161-169 (1999)
Simultaneous Determination of (-)-Menthone and (-)-Menthol in Menthae Herba by Gas Chromatography and Principal Component Analysis
Kim HS, et al.
Natural Product Sciences, 16(3), 180-184 (2010)
Vivian Tullio et al.
Molecules (Basel, Switzerland), 24(17) (2019-09-01)
The promising antimicrobial activity of essential oils (EOs) has led researchers to use them in combination with antimicrobial drugs in order to reduce drug toxicity, side effects, and resistance to single agents. Mentha x piperita, known worldwide as "Mentha of
Guanying Hu et al.
International immunopharmacology, 24(2), 191-197 (2014-12-17)
Danshu capsule (DSC) is a medicinal compound in traditional Chinese medicine (TCM). It is commonly used for the treatment of acute & chronic cholecystitis as well as choleithiasis. To study its choleretic effect, healthy rats were randomly divided into DSC
View All Related Papers

Protocols

GC Analysis of Geranium Bourbon Essential Oil on SUPELCOWAX® 10

-(+)-Limonene, purum, ≥98.0% (sum of enantiomers, GC); Geranyl tiglate; α-Terpineol, natural, ≥96%, FCC, FG; Geranyl formate; α-Pinene

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