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D-Sorbitol

Name: <SC>D</SC>-Sorbitol
Brand: SIAL

liquid, tested according to Ph. Eur.

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Synonym(s):

Sorbitolum liquidum non cristallisabile, D-Glucitol

Empirical Formula (Hill Notation):

C₆H₁₄O₆

CAS Number:

50-70-4

Molecular Weight:

182.17

Beilstein:

1721899

EC Number:

200-061-5

MDL number:

MFCD00004708

PubChem Substance ID:

329770356

NACRES:

NA.21

Agency

USP/NF
tested according to Ph. Eur.

Quality Level

100

vapor density

<1 (vs air)

vapor pressure

<0.1 mmHg ( 25 °C)

Assay

72-92%

form

liquid

impurities

28-32% water

color

white

useful pH range

5.0-7 (25 °C, 182 g/L)

mp

98-100 °C (lit.)

solubility

water: soluble 182 g/L at 20 °C (68 °F)

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m1/s1

InChI key

FBPFZTCFMRRESA-JGWLITMVSA-N

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Related Categories

Carbohydrates for Biochemical Research

Other Notes

To gain a comprehensive understanding of our extensive range of Sugar alcohols for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Antibody-mediated growth inhibition of Plasmodium falciparum: relationship to age and protection from parasitemia in Kenyan children and adults.

Arlene E Dent et al.

PloS one, 3(10), e3557-e3557 (2008-10-30)

Antibodies that impair Plasmodium falciparum merozoite invasion and intraerythrocytic development are one of several mechanisms that mediate naturally acquired immunity to malaria. Attempts to correlate anti-malaria antibodies with risk of infection and morbidity have yielded inconsistent results. Growth inhibition assays

Tolrestat pharmacokinetic and pharmacodynamic effects on red blood cell sorbitol levels in normal volunteers and in patients with insulin-dependent diabetes.

J M van Griensven et al.

Clinical pharmacology and therapeutics, 58(6), 631-640 (1995-12-01)

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The phosphoinositide PI(3,5)P₂ mediates activation of mammalian but not plant TPC proteins: functional expression of endolysosomal channels in yeast and plant cells.

Anna Boccaccio et al.

Cellular and molecular life sciences : CMLS, 71(21), 4275-4283 (2014-04-29)

Two-pore channel proteins (TPC) encode intracellular ion channels in both animals and plants. In mammalian cells, the two isoforms (TPC1 and TPC2) localize to the endo-lysosomal compartment, whereas the plant TPC1 protein is targeted to the membrane surrounding the large

Small molecule targeting malaria merozoite surface protein-1 (MSP-1) prevents host invasion of divergent plasmodial species.

Rajesh Chandramohanadas et al.

The Journal of infectious diseases, 210(10), 1616-1626 (2014-05-28)

Malaria causes nearly 1 million deaths annually. Recent emergence of multidrug resistance highlights the need to develop novel therapeutic interventions against human malaria. Given the involvement of sugar binding plasmodial proteins in host invasion, we set out to identify such

Novel D-xylose derivatives stimulate muscle glucose uptake by activating AMP-activated protein kinase alpha.

Arie Gruzman et al.

Journal of medicinal chemistry, 51(24), 8096-8108 (2008-12-04)

Type 2 diabetes mellitus has reached epidemic proportions; therefore, the search for novel antihyperglycemic drugs is intense. We have discovered that D-xylose increases the rate of glucose transport in a non-insulin-dependent manner in rat and human myotubes in vitro. Due

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