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A0800000

Amoxicillin trihydrate

European Pharmacopoeia (EP) Reference Standard

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About This Item

Empirical Formula (Hill Notation):
C16H19N3O5S · 3H2O
CAS Number:
61336-70-7
Molecular Weight:
419.45
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329770631
MDL number:
MFCD00072029
Beilstein/REAXYS Number:
7507120

Key Documents

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Product Name

Amoxicillin trihydrate, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C16H19N3O5S.3H2O/c1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7;;;/h3-6,9-11,14,20H,17H2,1-2H3,(H,18,21)(H,23,24);3*1H2/t9-,10-,11+,14-;;;/m1.../s1

SMILES string

O.O.O.CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C(=O)N2[C@H]1C(O)=O

InChI key

MQXQVCLAUDMCEF-CWLIKTDRSA-N

grade

pharmaceutical primary standard

agency

EP

API family

amoxicillin

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Application

Amoxicillin trihydrate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H317,H334

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

涉药品监管产品
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Katherine E Fleming-Dutra et al.
Pediatrics, 134(6), 1059-1066 (2014-11-19)
Previous research suggests that physicians may be less likely to diagnose otitis media (OM) and to prescribe broad-spectrum antibiotics for black versus nonblack children. Our objective was to determine whether race is associated with differences in OM diagnosis and antibiotic
Clinical trial evidence to advance the science of cholecystectomy.
Joseph S Solomkin
JAMA, 312(2), 135-136 (2014-07-10)
Jean Marc Regimbeau et al.
JAMA, 312(2), 145-154 (2014-07-10)
Ninety percent of cases of acute calculous cholecystitis are of mild (grade I) or moderate (grade II) severity. Although the preoperative and intraoperative antibiotic management of acute calculous cholecystitis has been standardized, few data exist on the utility of postoperative
Gilson C N Franco et al.
International journal of clinical pharmacology and therapeutics, 52(5), 425-430 (2014-04-24)
To compare the pharmacokinetic profiles and to evaluate the bioequivalence of two commercial amoxicillin suspension formulations (500 mg/5 mL AMOXIL®, reference formulation and AMOXI-PED®, test formulation) in healthy Brazilian volunteers. Under fasting condition, 25 volunteers (13 males and 12 females)
Salomone Di Saverio et al.
Annals of surgery, 260(1), 109-117 (2014-03-22)
To assess the safety and efficacy of antibiotics treatment for suspected acute uncomplicated appendicitis and to monitor the long term follow-up of non-operated patients. Right lower quadrant abdominal pain is a common cause of emergency department admission. The natural history
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