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A1202000

Citric acid

anhydrous, European Pharmacopoeia (EP) Reference Standard

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About This Item

Linear Formula:
HOC(COOH)(CH2COOH)2
CAS Number:
77-92-9
Molecular Weight:
192.12
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329770684
MDL number:
MFCD00011669
Beilstein/REAXYS Number:
782061

Key Documents

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Product Name

Citric acid, anhydrous, European Pharmacopoeia (EP) Reference Standard

InChI key

KRKNYBCHXYNGOX-UHFFFAOYSA-N

SMILES string

OC(=O)CC(O)(CC(O)=O)C(O)=O

InChI

1S/C6H8O7/c7-3(8)1-6(13,5(11)12)2-4(9)10/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

grade

pharmaceutical primary standard

agency

EP reference standard

API family

citric acid

quality

anhydrous

expl. lim.

8 %, 65 °F

manufacturer/tradename

EDQM

pKa 

(1) 3.13, (2) 4.76, (3) 6.4

mp

153-159 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Application

Citric acid EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H319,H335

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Giampiero Rossi-Fedele et al.
Journal of endodontics, 38(4), 426-431 (2012-03-15)
Root canal irrigants play a significant role in the elimination of microorganisms, tissue dissolution, and the removal of debris and smear layer. No single solution is able to fulfill these actions completely; therefore, their association is required. The aim of
Levente Karaffa et al.
Applied microbiology and biotechnology, 61(3), 189-196 (2003-04-17)
This Mini-Review summarizes the current knowledge on the biochemical and physiological events leading to massive citric acid accumulation by Aspergillus niger under industrially comparable conditions, thereby particularly emphasizing the roles of glycolytic flux and its control, excretion of citric acid
Nadia J Brown et al.
Burns : journal of the International Society for Burn Injuries, 40(5), 887-895 (2014-01-18)
Burns and their associated wound care procedures evoke significant stress and anxiety, particularly for children. Little is known about the body's physiological stress reactions throughout the stages of re-epithelialization following an acute burn injury. Previously, serum and urinary cortisol have
Wei-An Lai et al.
Journal of molecular endocrinology, 53(2), 259-270 (2014-07-25)
Estrogens are essential for female reproduction and overall well-being, and estrogens in the circulation are largely synthesized in ovarian granulosa cells. Using primary cultures of ovarian granulosa cells from gonadotropin-primed immature rats, we have recently discovered that pituitary FSH and
Yohei Nakayama et al.
Journal of oral science, 56(4), 261-268 (2014-12-17)
Amelotin (AMTN) is a secreted protein transcribed predominantly during the maturation stage of enamel formation and localized in the junctional epithelium. We investigated differences in the levels of AMTN gene expression between non-inflamed gingiva and inflamed gingiva from patients with
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