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A4382

Sigma-Aldrich

4-Aminoantipyrine

reagent grade

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Synonym(s):
4-Amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one, Ampyrone
Empirical Formula (Hill Notation):
C11H13N3O
CAS Number:
83-07-8
Molecular Weight:
203.24
Beilstein:
181635
EC Number:
201-452-3
MDL number:
MFCD00003145
PubChem Substance ID:
24890855
NACRES:
NA.31

grade

reagent grade

Quality Level

300

Assay

≥97% (HPLC)

form

powder

mp

105-110 °C (lit.)

solubility

water: 50 mg/mL

SMILES string

CN1N(c2ccccc2)C(=O)C(N)=C1C

InChI

1S/C11H13N3O/c1-8-10(12)11(15)14(13(8)2)9-6-4-3-5-7-9/h3-7H,12H2,1-2H3

InChI key

RLFWWDJHLFCNIJ-UHFFFAOYSA-N

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Application

Reagent for glucose determination in the presence of phenol and peroxidase.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Yue Teng et al.
Journal of hazardous materials, 190(1-3), 574-581 (2011-04-19)
4-Aminoantipyrine (AAP) is widely used in the pharmaceutical industry, in biochemical experiments and in environmental monitoring. AAP as an aromatic pollutant in the environment poses a great threat to human health. To evaluate the toxicity of AAP at the protein
A Z El-Sonbati et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 104, 213-221 (2012-12-27)
A novel series of copper(II) and palladium(II) with 4-derivatives benzaldehyde pyrazolone (L(n)) were synthesized. The mixed ligand complexes were prepared by using 1,10-phenanthroline (Phen) as second ligand. The structure of these complexes was identified and confirm by elemental analysis, molar
N Raman et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 85(1), 223-234 (2011-10-25)
Few novel 4-aminoantipyrine derived Schiff bases and their metal complexes were synthesized and characterized. Their structural features and other properties were deduced from the elemental analysis, magnetic susceptibility and molar conductivity as well as from mass, IR, UV-vis, (1)H NMR
Isela Lavilla et al.
Talanta, 98, 197-202 (2012-09-04)
In this work, a new method based on the combination of dispersive liquid-liquid microextraction (DLLME) with microvolume spectrophotometry has been developed as a greener and miniaturized alternative to the 5530 APHA standard method for determining phenols in water and wastewater.
Yue Teng et al.
Journal of hazardous materials, 192(3), 1766-1771 (2011-07-26)
The effects of 4-aminoantipyrine (AAP) on oxidative stress induced by glutathione (GSH) depletion in single human erythrocytes were investigated using microfluidic technique and fluorescence imaging. Most cell-based toxicity evaluations on GSH are performed with bulk experiments based on analysis of
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