A9797
Ambroxol hydrochloride
analytical standard
Synonym(s):
2-Amino-3,5-dibromo-N-(trans-4-hydroxycyclohexyl)benzylamine
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About This Item
Empirical Formula (Hill Notation):
C13H18Br2N2O · HCl
CAS Number:
Molecular Weight:
414.56
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
245-899-2
MDL number:
grade
analytical standard
Quality Segment
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
storage temp.
2-8°C
SMILES string
Cl.Nc1c(Br)cc(Br)cc1CN[C@@H]2CC[C@@H](O)CC2
InChI
1S/C13H18Br2N2O.ClH/c14-9-5-8(13(16)12(15)6-9)7-17-10-1-3-11(18)4-2-10;/h5-6,10-11,17-18H,1-4,7,16H2;1H/t10-,11-;
InChI key
QNVKOSLOVOTXKF-PFWPSKEQSA-N
General description
Ambroxol hydrochloride is a mucolytic expectorant and a metabolite of bromhexine. It is used in the treatment of respiratory disorders characterized by viscous or excessive mucus.
Application
Ambroxol hydrochloride standard may be used as a reference standard in the determination of ambroxol hydrochloride in pharmaceutical preparations using reversed-phase sequential injection chromatography (RP-SIC) and reversed-phase high performance liquid chromatography (RP-HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
Metabolite of bromhexine.
A Nav1.8-preferring sodium channel blocker
A Nav1.8-preferring sodium channel blocker
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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