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Merck
CN

B0250000

Bambuterol hydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Dimethylcarbmic acid 5-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]-1,3-phenylene ester

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About This Item

Linear Formula:
C18H29N3O5 · HCl
CAS Number:
81732-46-9
Molecular Weight:
403.90
NACRES:
NA.24
PubChem Substance ID:
329773104
UNSPSC Code:
41116107
MDL number:
MFCD03427293

Key Documents

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Product Name

Bambuterol hydrochloride, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C18H29N3O5.ClH/c1-18(2,3)19-11-15(22)12-8-13(25-16(23)20(4)5)10-14(9-12)26-17(24)21(6)7;/h8-10,15,19,22H,11H2,1-7H3;1H

SMILES string

Cl.CN(C)C(=O)Oc1cc(OC(=O)N(C)C)cc(c1)C(O)CNC(C)(C)C

InChI key

LBARATORRVNNQM-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

bambuterol

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Related Categories

Application

Bambuterol hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

β-adrenoceptor agonist; bronchodilator; anti-asthmatic; terbutaline prodrug

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Ting Zhou et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 967, 225-234 (2014-08-17)
In this study, a rapid and sensitive hydrophilic interaction ultra-performance liquid chromatography-tandem mass spectrometry (HILIC-UPLC-MS/MS) method was developed for simultaneous determination of bambuterol and its two major metabolites monocarbamate bambuterol and terbutaline in human plasma. All samples were simply precipitated

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