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Merck
CN

B4252

5-Bromo-4-chloro-3-indolyl β-D-galactopyranoside

chromogenic, ≥98%, powder

Synonym(s):

5-Bromo-4-chloro-3-indolyl β-D-galactoside, BCIG, X-Gal

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About This Item

Empirical Formula (Hill Notation):
C14H15BrClNO6
CAS Number:
Molecular Weight:
408.63
NACRES:
NA.83
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
230-640-8
MDL number:
Beilstein/REAXYS Number:
1402009
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Product Name

5-Bromo-4-chloro-3-indolyl β-D-galactopyranoside, ≥98%, powder

Quality Level

assay

≥98%

form

powder

solubility

DMF: methanol (1:1): 50 mg/mL

storage temp.

−20°C

SMILES string

OC[C@H]1O[C@@H](Oc2c[nH]c3ccc(Br)c(Cl)c23)[C@H](O)[C@@H](O)[C@H]1O

InChI

1S/C14H15BrClNO6/c15-5-1-2-6-9(10(5)16)7(3-17-6)22-14-13(21)12(20)11(19)8(4-18)23-14/h1-3,8,11-14,17-21H,4H2/t8-,11+,12+,13-,14-/m1/s1

InChI key

OPIFSICVWOWJMJ-AEOCFKNESA-N

Application

X-Gal is a chromogenic substrate for β-galactosidase that produces a rich blue color that can easily be detected visually over background. X-Gal is the substrate of choice for blue-white selection of recombinant bacterial colonies with the lac+ genotype.


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

涉药品监管产品

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Diana Klein et al.
Antioxidants & redox signaling, 24(2), 53-69 (2015-06-13)
Previous thorax irradiation promotes metastatic spread of tumor cells to the lung. We hypothesized that vascular damage facilitates lung metastasis after thorax irradiation and that therapeutically applied multipotent mesenchymal stromal cells (MSCs) with reported repair activity may prevent these adverse
Carina Henning et al.
Scientific reports, 9(1), 16931-16931 (2019-11-16)
An acute increase in blood flow triggers flow-mediated dilation (FMD), which is mainly mediated by endothelial nitric oxide synthase (eNOS). A long-term increase in blood flow chronically enlarges the arterial lumen, a process called arteriogenesis. In several common human diseases



Global Trade Item Number

SKUGTIN
B4252-2G04061833616550
B4252-500MG04061833429419
B4252-5G04061833429426
B4252-1G04061835480234
B4252-250MG04061835553792
B4252-100MG04061835540693
B4252-50MG04061835553808