Skip to Content
Merck
CN

B5775

Bendroflumethiazide

analytical standard

Synonym(s):

3-Benzyl-6-trifluoromethyl-7-sulfamoyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C15H14F3N3O4S2
CAS Number:
73-48-3
Molecular Weight:
421.41
NACRES:
NA.24
PubChem Substance ID:
329773267
UNSPSC Code:
41116107
EC Number:
200-800-1
MDL number:
MFCD00078963

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

InChI

1S/C15H14F3N3O4S2/c16-15(17,18)10-7-11-13(8-12(10)26(19,22)23)27(24,25)21-14(20-11)6-9-4-2-1-3-5-9/h1-5,7-8,14,20-21H,6H2,(H2,19,22,23)

InChI key

HDWIHXWEUNVBIY-UHFFFAOYSA-N

SMILES string

NS(=O)(=O)c1cc2c(NC(Cc3ccccc3)NS2(=O)=O)cc1C(F)(F)F

grade

analytical standard

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

Quality Level

200

Gene Information

human ... SLC12A3(6559)

Looking for similar products? Visit Product Comparison Guide

General description

Bendroflumethiazide belongs to the class of thiazide diuretics, widely used in enhancing diuresis. It is also used as an effective antihypertensive agent and in the treatment of edema caused by cardiac/renal failure and myocardial infarction. Its mode of action involves increasing the urine flow and the net renal excretion of both sodium and water.

Application

Bendroflumethiazide may be used as an analytical reference standard for the quantification of the analyte in pharmaceutical formulations using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

监管及禁止进口产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000293837
0000293837
079F1025V
079F1025

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Analysis of diuretic doping agents by HPLC screening and GC?MSD confirmation
Tsai Y-F, et al.
Journal of Pharmaceutical and Biomedical Analysis, 9(10-12), 1069-1076 (1991)
D Tricarico et al.
British journal of pharmacology, 154(1), 183-190 (2008-03-18)
Acetazolamide and dichlorphenamide are carbonic anhydrase (CA) inhibitors effective in the clinical condition of hypokalemic periodic paralysis (hypoPP). Whether these drugs prevent vacuolar myopathy, which is a pathogenic factor in hypoPP, is unknown. The effects of these drugs on the
Naila Rabbani et al.
Amino acids, 42(5), 1627-1639 (2011-03-09)
The aim of this study was to assess the effect of the angiotensin II receptor blocker Irbesartan on protein damage by glycation, oxidation and nitration in patients with type 2 diabetes and microalbuminuria. In a double-masked randomised crossover trial of
Ajay K Gupta et al.
Journal of hypertension, 29(10), 2004-2013 (2011-09-02)
Resistant hypertension is a well recognized clinical entity, which has been inadequately researched to date. A multivariable Cox model was developed to identify baseline predictors of developing resistant hypertension among 3666 previously untreated Anglo-Scandinavian Cardiac Outcome Trial (ASCOT) patients and
Neil R Poulter et al.
Journal of the American College of Cardiology, 54(13), 1154-1161 (2009-09-19)
The aim of this study was to evaluate the effect of baseline heart rate on the efficacy of atenolol-based compared with amlodipine-based therapy in patients with hypertension uncomplicated by coronary heart disease in the ASCOT-BPLA (Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service