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Sigma-Aldrich

Benoxinate hydrochloride

meets USP testing specifications

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Synonym(s):
2-(Diethylamino)ethyl 4-amino-3-butoxybenzoate hydrochloride, 4-Amino-3-butoxybenzoic acid diethylaminoethyl ester, Oxybuprocaine hydrochloride
Empirical Formula (Hill Notation):
C17H28N2O3 · HCl
CAS Number:
5987-82-6
Molecular Weight:
344.88
EC Number:
227-808-8
MDL number:
MFCD00012512
PubChem Substance ID:
24892118
NACRES:
NA.21

Agency

USP/NF
meets USP testing specifications

Quality Level

200

form

solid

application(s)

pharmaceutical (small molecule)

SMILES string

Cl[H].CCCCOc1cc(ccc1N)C(=O)OCCN(CC)CC

InChI

1S/C17H28N2O3.ClH/c1-4-7-11-21-16-13-14(8-9-15(16)18)17(20)22-12-10-19(5-2)6-3;/h8-9,13H,4-7,10-12,18H2,1-3H3;1H

InChI key

PRGUDWLMFLCODA-UHFFFAOYSA-N

Gene Information

human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

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Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Neal E Mecum et al.
Scientific reports, 10(1), 17225-17225 (2020-10-16)
Lacrimal gland excision (LGE) induced dry eye produces more severe corneal damage in female mice, yet signs of LGE-induced ocular pain and anxiety in male and female mice have not been characterized. Excision of either the extraorbital gland (single LGE)
Minako Kaido et al.
Japanese journal of ophthalmology, 55(5), 451-459 (2011-07-01)
To investigate the relation of functional visual acuity (FVA) measurements with dry eye test parameters and to compare the testing methods with and without blink suppression and anesthetic instillation. A prospective comparative case series. Thirty right eyes of 30 dry
Jaime Tejedor et al.
Ophthalmology, 117(10), 1883-1888 (2010-06-24)
To compare a surgically adjusted dose of strabismus surgery using topical anesthesia in cooperative patients with dosage guidelines adapted to the surgeon's personal technique using sub-Tenon's anesthesia. Randomized, controlled, single-site clinical trial. Sixty patients with nonparalytic, nonrestrictive esotropia who were
Robin K Harris et al.
Physical chemistry chemical physics : PCCP, 9(3), 360-368 (2007-01-03)
The (13)C CPMAS spectrum is presented for the polymorph of oxybuprocaine hydrochloride which is stable at room temperature, i.e. Mod. II degrees . It shows crystallographic splittings arising from the fact that there are two molecules, with substantially different conformations
Nicola Rosa et al.
Optometry and vision science : official publication of the American Academy of Optometry, 88(5), 640-644 (2011-03-02)
To investigate the effect of oxybuprocaine eye drops on corneal volume (CV) and corneal thickness measurements. Central corneal thickness (CCT), corneal thinnest point (CTP), and CV of 78 eyes of 78 healthy volunteers were measured with Pentacam, before and 5
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