Skip to Content
Merck
CN

BP197

Hydroxycarbamide

British Pharmacopoeia (BP) Reference Standard

Synonym(s):

Hydroxyurea, Hydroxycarbamide

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Linear Formula:
NH2CONHOH
CAS Number:
127-07-1
Molecular Weight:
76.05
NACRES:
NA.24
UNSPSC Code:
41116107
Beilstein/REAXYS Number:
1741548
MDL number:
MFCD00007943

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Hydroxycarbamide, British Pharmacopoeia (BP) Reference Standard

SMILES string

NC(=O)NO

InChI key

VSNHCAURESNICA-UHFFFAOYSA-N

InChI

1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4)

grade

pharmaceutical primary standard

API family

hydroxycarbamide

form

solid

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

application(s)

pharmaceutical
pharmaceutical small molecule

format

neat

storage temp.

2-8°C

Gene Information

human ... RRM1(6240), RRM2(6241), RRM2B(50484)

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

Hydroxycarbamide BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Hydroxycarbamide Capsules

    • Biochem/physiol Actions

    Anti-neoplastic. Inactivates ribonucleoside reductase by forming a free radical nitroxide that binds a tyrosyl free radical in the active site of the enzyme. This blocks the synthesis of deoxynucleotides, which inhibits DNA synthesis and induces synchronization or cell death in S-phase.

    General description

    This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

    Other Notes

    Sales restrictions may apply.

    Packaging

    Unit quantity: 200 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    pictograms

    Health hazard
    GHS08

    signalword

    Danger

    hcodes

    H340,H361

    Hazard Classifications

    Muta. 1B - Repr. 2

    Storage Class

    6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

    wgk

    WGK 3

    flash_point_f

    Not applicable

    flash_point_c

    Not applicable

    Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number

    It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

    If you need assistance, please contact Customer Support

    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

    Visit the Document Library

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service