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BP619

Diclofenac sodium

British Pharmacopoeia (BP) Reference Standard

Synonym(s):

Diclofenac sodium salt, 2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid sodium salt

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About This Item

Empirical Formula (Hill Notation):
C14H10Cl2NNaO2
CAS Number:
15307-79-6
Molecular Weight:
318.13
UNSPSC Code:
41116107
NACRES:
NA.24
EC Number:
239-346-4
MDL number:
MFCD00082251

Key Documents

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Product Name

Diclofenac sodium, British Pharmacopoeia (BP) Reference Standard

InChI key

KPHWPUGNDIVLNH-UHFFFAOYSA-M

InChI

1S/C14H11Cl2NO2.Na/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19;/h1-7,17H,8H2,(H,18,19);/q;+1/p-1

SMILES string

[Na+].[O-]C(=O)Cc1ccccc1Nc2c(Cl)cccc2Cl

grade

pharmaceutical primary standard

API family

diclofenac

form

solid

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

application(s)

pharmaceutical (small molecule)
pharmaceutical
pharmaceutical small molecule

format

neat

storage temp.

2-8°C

Gene Information

human ... PTGS1(5742), PTGS2(5743)

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Application

Diclofenac sodium BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Diclofenac Diethylamine Gel
  • Diclofenac Prolonged-release Tablets
  • Diclofenac Gastro-resistant Tablets
  • Diclofenac Prolonged-release Capsules

    • Biochem/physiol Actions

    Standard NSAID and cyclooxygenase (COX) inhibitor. Major metabolites are 4´-hydroxydiclofenac and 5´-hydroxydiclofenac. Has been used as substrate selective for CYP2C9.

    General description

    This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

    Other Notes

    Sales restrictions may apply.
    Learn how British Pharmacopoeia (BP) sets the standard by offering quality British Pharmacopoeia Chemical Reference Substances (BPCRS).

    Packaging

    Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    signalword

    Danger

    Hazard Classifications

    Acute Tox. 3 Oral - Aquatic Chronic 2 - Repr. 2 - STOT RE 1

    Storage Class

    6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

    wgk

    WGK 3

    flash_point_f

    Not applicable

    flash_point_c

    Not applicable

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