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BP882

α-Tocopherol

British Pharmacopoeia (BP) Reference Standard

Synonym(s):

(±)-α-Tocopherol, DL-all-rac-α-Tocopherol, Vitamin E

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About This Item

Empirical Formula (Hill Notation):
C29H50O2
CAS Number:
10191-41-0
Molecular Weight:
430.71
EC Number:
233-466-0
UNSPSC Code:
41116107
NACRES:
NA.24
Beilstein/REAXYS Number:
94012
MDL number:
MFCD00006848

Key Documents

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Product Name

α-Tocopherol, British Pharmacopoeia (BP) Reference Standard

InChI key

GVJHHUAWPYXKBD-UHFFFAOYSA-N

InChI

1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3

SMILES string

CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(O)c(C)c(C)c2O1

grade

pharmaceutical primary standard

API family

tocopherol

form

solid

manufacturer/tradename

BP

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

color

light yellow

mp

2.5-3.5 °C

density

0.950 g/mL at 20 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Application

Α-Tocopherol BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Alpha Tocopheryl Succinate Tablets

    • General description

    This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia. α -Tocopherol is the active form of vitamin E. It functions as an hydroperoxyl radical scavenger and protects from oxidative damage. α -Tocopherol plays a crucial role in cell signalling and regulating immune responses. α -Tocopherol deficiency is associated with abetalipoproteinemia, cystic fibrosis and celiac disease. It has antiproliferative effects. It inhibits arsenite-induced damage of human fibroblasts.

    Other Notes

    Sales restrictions may apply.
    Learn how British Pharmacopoeia (BP) sets the standard by offering quality British Pharmacopoeia Chemical Reference Substances (BPCRS).

    Packaging

    Unit quantity: 200 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    pictograms

    Exclamation mark
    GHS07

    signalword

    Warning

    hcodes

    H317

    Hazard Classifications

    Skin Sens. 1

    Storage Class

    10 - Combustible liquids

    wgk

    WGK 1

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    Simultaneous determination of retinol, α-tocopherol and β-carotene in serum by isocratic high-performance liquid chromatography
    Arnaud J, et al.
    Journal of Chromatography. B, Biomedical Sciences and Applications, 572(1-2), 103-116 (1991)

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