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C1290

Supelco

Chlorpropamide

analytical standard, ≥97%

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Synonym(s):
1-(p-Chlorobenzenesulfonyl)-3-propylurea
Empirical Formula (Hill Notation):
C10H13ClN2O3S
CAS Number:
Molecular Weight:
276.74
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

Assay

≥97%

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CCCNC(=O)NS(=O)(=O)c1ccc(Cl)cc1

InChI

1S/C10H13ClN2O3S/c1-2-7-12-10(14)13-17(15,16)9-5-3-8(11)4-6-9/h3-6H,2,7H2,1H3,(H2,12,13,14)

InChI key

RKWGIWYCVPQPMF-UHFFFAOYSA-N

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General description

Chlorpropamide is a drug that belongs to the sulfonylurea family. It is an effective candidate in the treatment of diabetes insipidus.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Exclamation markHealth hazard

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Worst Pills, Best Pills: A Consumer's Guide to Preventing Drug-Induced Deat (2009)
Advances in Clinical Chemistry, Volume 17 (1975)
Qing Zhu et al.
Molecular pharmaceutics, 7(4), 1291-1300 (2010-06-17)
As a result of an increase in the number of emerging therapies with dissolution limited bioavailability, formulation strategies such as solid dispersions that enhance the rate of solubilization are of interest. In this study, the microstructure of solid dispersions prepared
Tsutomu Shimura et al.
International journal of radiation oncology, biology, physics, 80(2), 540-548 (2011-03-15)
Radioresistance is a major cause of treatment failure of radiotherapy (RT) in human cancer. We have recently revealed that acquired radioresistance of tumor cells induced by fractionated radiation is attributable to cyclin D1 overexpression as a consequence of the downregulation
Terence M Williams et al.
Molecular cancer therapeutics, 11(5), 1193-1202 (2012-03-14)
There is an urgent need for the development of novel therapies to treat pancreatic cancer, which is among the most lethal of all cancers. KRAS-activating mutations, which are found in more than 90% of pancreatic adenocarcinomas, drive tumor dependency on

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