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Merck
CN

C1915

Chloropyramine hydrochloride

analytical standard, for drug analysis

Synonym(s):

N-p-Chlorobenzyl-N′,N′-dimethyl-N-(2-pyridyl)ethylenediamine

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About This Item

Empirical Formula (Hill Notation):
C16H20ClN3 · HCl
CAS Number:
Molecular Weight:
326.26
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
228-216-2
MDL number:
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Product Name

Chloropyramine hydrochloride, analytical standard, for drug analysis

InChI key

VEYWWAGBHABATA-UHFFFAOYSA-N

InChI

1S/C16H20ClN3.ClH/c1-19(2)11-12-20(16-5-3-4-10-18-16)13-14-6-8-15(17)9-7-14;/h3-10H,11-13H2,1-2H3;1H

SMILES string

Cl.CN(C)CCN(Cc1ccc(Cl)cc1)c2ccccn2

grade

analytical standard

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

Quality Level

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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W Durand-Arczynska et al.
Journal de physiologie, 81(3), 185-190 (1986-01-01)
The effects on transepithelial ion transports of chloropyramine, dimetindene and diphenhydramine, which are three antagonists of H1-receptors of histamine, were examined in bovine tracheal epithelium and in frog skin. The short-circuit current I0 across bovine tracheal epithelium is the sum
K I Bender et al.
Farmakologiia i toksikologiia, 52(3), 66-71 (1989-05-01)
In the experiments on male albino rats absorption of dimedrol, pipolphen and suprastin from the small intestine was studied in vitro by the method of "turned sacks". It was shown that immunization of the animals with ovalbumin in combination with
A Györfi et al.
Agents and actions, 32(3-4), 229-236 (1991-03-01)
The mechanism of development of neurogenic inflammatory reaction induced by the topical application of capsaicin was studied in the oral mucosa of rats with or without histamine antagonist pretreatment. The existence of a cholinergic component of the vasodilation was investigated
Kinetics of injected histamine in cat plasma after antihistamine prophylaxis.
T Irman-Florjanc
Inflammation research : official journal of the European Histamine Research Society ... [et al.], 49 Suppl 1, S74-S75 (2000-06-23)
P Rajna et al.
Therapia Hungarica (English edition), 42(1), 14-20 (1994-01-01)
In order to assess the effects of Loderix (setastine) on the EEG ten healthy male volunteers were investigated in double-blind, placebo-controlled, cross-over arrangement. In addition to the test compound (Loderix) volunteers were treated with vehicle and with two referent drugs

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