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Merck
CN

C1915

Chloropyramine hydrochloride

analytical standard, for drug analysis

Synonym(s):

N-p-Chlorobenzyl-N′,N′-dimethyl-N-(2-pyridyl)ethylenediamine

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About This Item

Empirical Formula (Hill Notation):
C16H20ClN3 · HCl
CAS Number:
Molecular Weight:
326.26
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
228-216-2
MDL number:
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InChI key

VEYWWAGBHABATA-UHFFFAOYSA-N

InChI

1S/C16H20ClN3.ClH/c1-19(2)11-12-20(16-5-3-4-10-18-16)13-14-6-8-15(17)9-7-14;/h3-10H,11-13H2,1-2H3;1H

SMILES string

Cl.CN(C)CCN(Cc1ccc(Cl)cc1)c2ccccn2

grade

analytical standard

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

Quality Level

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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D B Beleslin et al.
Neuropharmacology, 26(8), 1157-1165 (1987-08-01)
The emetic action of noradrenaline was investigated in unanesthetized cats, after it was injected into the cerebral ventricles through chronically implanted cannulae. Intracerebroventricular injection of noradrenaline produced dose-dependent and shortlasting emesis, which was abolished after ablation of the area postrema.
[Application of aqueous Eudragit dispersions to the preparation of controlled release oral antihistamine dosage forms].
A Dévay et al.
Acta pharmaceutica Hungarica, 58(4), 166-172 (1988-07-01)
M Budihna et al.
Pflugers Archiv : European journal of physiology, 431(6 Suppl 2), R217-R218 (1996-01-01)
In isolated rat hearts effects of chloropyramine (CP), histamine H1 antagonist, and famotidine (FA), H2 antagonist, upon two different myocardial injuries, ischaemia-reperfusion and hypoxia-reoxygenation were studied. In both types of injury the effects of drugs were seen mainly during reperfusion
[Toxico-allergic form of erythema multiforme exudativum caused by suprastin].
S M Fedorov et al.
Vestnik dermatologii i venerologii, (9)(9), 50-51 (1986-01-01)
A Györfi et al.
Agents and actions, 32(3-4), 229-236 (1991-03-01)
The mechanism of development of neurogenic inflammatory reaction induced by the topical application of capsaicin was studied in the oral mucosa of rats with or without histamine antagonist pretreatment. The existence of a cholinergic component of the vasodilation was investigated

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