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Merck
CN

C1915000

Chlorprothixene hydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

2-Chloro-9-(3-dimethylaminopropylidene)thioxanthene hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C18H18ClNS · HCl
CAS Number:
6469-93-8
Molecular Weight:
352.32
NACRES:
NA.24
PubChem Substance ID:
329774917
UNSPSC Code:
41116107
MDL number:
MFCD01941605

Key Documents

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Product Name

Chlorprothixene hydrochloride, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C18H18ClNS.ClH/c1-20(2)11-5-7-14-15-6-3-4-8-17(15)21-18-10-9-13(19)12-16(14)18;/h3-4,6-10,12H,5,11H2,1-2H3;1H/b14-7-;

SMILES string

Cl.CN(C)CC\C=C1\c2ccccc2Sc3ccc(Cl)cc13

InChI key

YWKRLOSRDGPEJR-KIUKIJHYSA-N

grade

pharmaceutical primary standard

API family

chlorprothixene

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Gene Information

human ... DRD2(1813), DRD3(1814), HTR2A(3356), HTR2C(3358)

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Related Categories

Application

Chlorprothixene hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Chloroquine was a cheap, extremely effective drug against Plasmodium falciparum until resistance arose. One approach to reversing resistance is the inhibition of chloroquine efflux from its site of action, the parasite digestive vacuole. Chloroquine accumulation studies have traditionally relied on

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