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Merck
CN

C2175500

Cimetidine hydrochloride

European Pharmacopoeia (EP) Reference Standard

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About This Item

Empirical Formula (Hill Notation):
C10H16N6S · HCl
CAS Number:
70059-30-2
Molecular Weight:
288.80
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329774973
MDL number:
MFCD01724314
Beilstein/REAXYS Number:
5668216

Key Documents

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Product Name

Cimetidine hydrochloride, European Pharmacopoeia (EP) Reference Standard

SMILES string

Cl.CN\C(NC#N)=N/CCSCc1nc[nH]c1C

InChI key

QJHCNBWLPSXHBL-UHFFFAOYSA-N

InChI

1S/C10H16N6S.ClH/c1-8-9(16-7-15-8)5-17-4-3-13-10(12-2)14-6-11;/h7H,3-5H2,1-2H3,(H,15,16)(H2,12,13,14);1H

grade

pharmaceutical primary standard

API family

cimetidine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Gene Information

human ... HRH2(3274)

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Application

Cimetidine hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Rieko Oshima et al.
Metabolism: clinical and experimental, 64(2), 296-304 (2014-12-01)
5'-Adenosine monophosphate-activated protein kinase (AMPK) is a key molecule of metabolic enhancement in skeletal muscle. We investigated whether metformin (MET) acts directly on skeletal muscle, is transported into skeletal muscle via organic cation transporters (OCTs), and activates AMPK. Isolated rat

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