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D0940

Sigma-Aldrich

p-Xylene-bis(N-pyridinium bromide)

≥95% (TLC)

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Synonym(s):
DPX
Empirical Formula (Hill Notation):
C18H18Br2N2
CAS Number:
Molecular Weight:
422.16
MDL number:
PubChem Substance ID:
NACRES:
NA.47

Quality Level

Assay

≥95% (TLC)

form

powder

color

white to off-white

solubility

H2O: soluble

εmax

8.6-9.2 at 256-262 nm in water

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

2-8°C

SMILES string

[Br-].[Br-].C(c1ccc(C[n+]2ccccc2)cc1)[n+]3ccccc3

InChI

1S/C18H18N2.2BrH/c1-3-11-19(12-4-1)15-17-7-9-18(10-8-17)16-20-13-5-2-6-14-20;;/h1-14H,15-16H2;2*1H/q+2;;/p-2

InChI key

MMKBQSJLLGHVIM-UHFFFAOYSA-L

Biochem/physiol Actions

Cationic fluorescence quencher used with ANTS to study membrane permeability and liposome lysis.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Elisabeth B Thubron et al.
Scientific reports, 9(1), 11386-11386 (2019-08-08)
Diabetes increases the risk of Alzheimer's disease (AD), and mitochondrial dysfunction is implicated in both diseases, however the impact of both diabetes and AD on brain mitochondria is not known. We measured mitochondrial DNA (mtDNA), an indicator of mitochondrial function
Jennifer A Ross et al.
Brain structure & function, 224(7), 2385-2405 (2019-06-30)
A culmination of evidence from the literature points to the Locus Coeruleus (LC)-Norepinephrine system as an underappreciated and understudied area of research in the context of Alzheimer's Disease (AD). Stress is a risk factor for developing AD, and is supported
Carolyn J Crandall et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 34(8), 1419-1427 (2019-03-29)
We examined among women aged ≥40 years the performance of the Fracture Risk Assessment Tool (FRAX) and FRAX-based osteoporosis treatment thresholds under the US National Osteoporosis Foundation (NOF) and UK National Osteoporosis Guideline Group (NOGG) guidelines. We used registry data
Elusa Cristina Oliveira et al.
Biology of reproduction, 100(3), 737-744 (2018-10-09)
Neonatal exposure to high-dose 17β-estradiol (E2) affects the morphology and physiology of sex and accessory sex organs in the long term. In this study, we examined the effects of E2 imprinting on male sexual behavior, fertility, and the number of
Thomas Walker et al.
Aging, 8(10), 2488-2508 (2016-10-16)
Despite regulation, brain iron increases with aging and may enhance aging processes including neuroinflammation. Increases in magnetic resonance imaging transverse relaxation rates, R2 and R2*, in the brain have been observed during aging. We show R2 and R2* correlate well

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