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Merck
CN

D2960000

Dopamine hydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

2-(3,4-Dihydroxyphenyl)ethylamine hydrochloride, 3,4-Dihydroxyphenethylamine hydrochloride, 3-Hydroxytyramine hydrochloride, 4-(2-Aminoethyl)-1,2-benzenediol hydrochloride

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About This Item

Linear Formula:
(HO)2C6H3CH2CH2NH2·HCl
CAS Number:
62-31-7
Molecular Weight:
189.64
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329798766
MDL number:
MFCD00012898
Beilstein/REAXYS Number:
3656720

Key Documents

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Product Name

Dopamine hydrochloride, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C8H11NO2.ClH/c9-4-3-6-1-2-7(10)8(11)5-6;/h1-2,5,10-11H,3-4,9H2;1H

SMILES string

Cl[H].NCCc1ccc(O)c(O)c1

InChI key

CTENFNNZBMHDDG-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

dopamine

manufacturer/tradename

EDQM

mp

248-250 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

Gene Information

human ... ADRB1(153)

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Application

Dopamine hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H317

Hazard Classifications

Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Adriana Basnakova et al.
Neurobiology of stress, 15, 100403-100403 (2021-10-12)
The response of an animal to a sensory stimulus depends on the nature of the stimulus and on expectations, which are mediated by spontaneous activity. Here, we ask how circadian variation in the expectation of danger, and thus the response
Hanneke E M den Ouden et al.
Neuron, 80(4), 1090-1100 (2013-11-26)
Serotonin and dopamine are speculated to subserve motivationally opponent functions, but this hypothesis has not been directly tested. We studied the role of these neurotransmitters in probabilistic reversal learning in nearly 700 individuals as a function of two polymorphisms in
Frank J Meye et al.
Trends in pharmacological sciences, 35(1), 31-40 (2013-12-18)
Overconsumption of high caloric food plays an important role in the etiology of obesity. Several factors drive such hedonic feeding. High caloric food is often palatable. In addition, when an individual is sated, stress and food-related cues can serve as
Sebastian C Holst et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(2), 566-573 (2014-01-10)
While dopamine affects fundamental brain processes such as movement control, emotional responses, addiction, and pain, the roles for this neurotransmitter in regulating wakefulness and sleep are incompletely understood. Genetically modified animal models with reduced dopamine clearance exhibit hypersensitivity to caffeine
Horng H Chen et al.
JAMA, 310(23), 2533-2543 (2013-11-20)
Small studies suggest that low-dose dopamine or low-dose nesiritide may enhance decongestion and preserve renal function in patients with acute heart failure and renal dysfunction; however, neither strategy has been rigorously tested. To test the 2 independent hypotheses that, compared
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