Skip to Content
Merck
CN

D6001

Dextran sulfate sodium salt from Leuconostoc spp.

average mol wt >500,000 (dextran starting material), contains 0.5-2.0% phosphate buffer, pH 6-8

Sign In to View Organizational & Contract Pricing.

Select a Size


About This Item

CAS Number:
UNSPSC Code:
12352201
NACRES:
NA.21
MDL number:
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Dextran sulfate sodium salt from Leuconostoc spp., average mol wt >500,000 (dextran starting material), contains 0.5-2.0% phosphate buffer, pH 6-8

useful pH range

6.0-8.0 (1% in water)

biological source

bacterial (Leuconostoc mesenteroides)

form

powder

optical activity

[α]/D 90 to 105 °, c = 6% (w/v) in water

mol wt

average mol wt >500,000 (dextran starting material)

contains

0.5-2.0% phosphate buffer, pH 6-8

composition

Sulfur Content, 16.0-19.0%

color

white to off-white

solubility

H2O: 100 mg/mL

Quality Level

Looking for similar products? Visit Product Comparison Guide

Application

Dextran sulfate sodium salt Leuconostoc spp has been used:
  • to delipidate fatty plasma(67)(70)
  • to induce inflammatory and carcinogenic response in the distal colon of rodents(68)
  • for the preparation of 3,4-ethylenedioxythiophene (EDOT)(69)

General description

Dextran sulfate is a negatively charged sulfated polysaccharide, which is produced by the esterification of dextran with chlorosulphonic acid. It has antiviral, anticoagulant and adjuvant properties. Dextran is used to treat hemorrhage, burns, surgery and trauma. It enhances blood flow and blocks erythrocyte aggregation. Dextran decreases the risk of thrombosis and postoperative pulmonary emboli. It acts as a ribonuclease inhibitor.

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Seda Onder et al.
Frontiers in pharmacology, 8, 713-713 (2017-10-27)
Hupresin is a new affinity resin that binds butyrylcholinesterase (BChE) in human plasma and acetylcholinesterase (AChE) solubilized from red blood cells (RBC). Hupresin is available from the CHEMFORASE company. BChE in human plasma binds to Hupresin and is released with
Zora Djuric et al.
The Journal of nutritional biochemistry, 46, 90-99 (2017-05-10)
Dietary fish oils have potential for prevention of colon cancer, and yet the mechanisms of action in normal and tumor colon tissues are not well defined. Here we evaluated the impact of the colonic fatty acid milieu on the formation
Radiotherapy, Surgery, and Immunotherapy (2012)
Delipidation of plasma has minimal effects on human butyrylcholinesterase
Onder S, et al.
Frontiers in Pharmacology, 9, 117-117 (2018)
The Molecular Biology of Poliovirus (2012)

Protocols

Dextran sulfates as sodium salts are water-soluble and stable, containing approximately 17% sulfur for various applications.

硫酸葡聚糖以钠盐形式供应,使其在水中可溶且稳定。硫酸葡聚糖含有大约17%的硫,相当于每个葡糖基残基大约有2.3个硫酸基团。

Related Content

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service