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D7770

Supelco

Diminazene aceturate

analytical standard

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Synonym(s):
Berenil
Empirical Formula (Hill Notation):
C14H15N7 · 2C4H7NO3
CAS Number:
908-54-3
Molecular Weight:
515.52
EC Number:
212-999-2
MDL number:
MFCD00058386
PubChem Substance ID:
329798786

grade

analytical standard

Quality Level

200

form

powder

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

CC(=O)NCC(O)=O.CC(=O)NCC(O)=O.NC(=N)c1ccc(N\N=N\c2ccc(cc2)C(N)=N)cc1

InChI

1S/C14H15N7.2C4H7NO3/c15-13(16)9-1-5-11(6-2-9)19-21-20-12-7-3-10(4-8-12)14(17)18;2*1-3(6)5-2-4(7)8/h1-8H,(H3,15,16)(H3,17,18)(H,19,20);2*2H2,1H3,(H,5,6)(H,7,8)

InChI key

OKQSSSVVBOUMNZ-UHFFFAOYSA-N

Related Categories

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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M Gysin et al.
International journal for parasitology. Drugs and drug resistance, 8(2), 159-164 (2018-03-28)
Trypanosoma congolense is a protozoan parasite that is transmitted by tsetse flies, causing African Animal Trypanosomiasis, also known as Nagana, in sub-Saharan Africa. Nagana is a fatal disease of livestock that causes severe economic losses. Two drugs are available, diminazene
Jia Yu Peppermint Lee et al.
British journal of pharmacology, 175(12), 2204-2218 (2017-11-15)
Acid-sensing ion channels (ASICs) are primary acid sensors in mammals, with the ASIC1b and ASIC3 subtypes being involved in peripheral nociception. The antiprotozoal drug diminazene is a moderately potent ASIC inhibitor, but its analgesic activity has not been assessed. We
Adam P Mecca et al.
Experimental physiology, 96(10), 1084-1096 (2011-06-21)
Activation of angiotensin-converting enzyme 2 (ACE2), production of angiotensin-(1-7) [Ang-(1-7)] and stimulation of the Ang-(1-7) receptor Mas exert beneficial actions in various peripheral cardiovascular diseases, largely through opposition of the deleterious effects of angiotensin II via its type 1 receptor.
Raqueli T França et al.
Veterinary clinical pathology, 42(1), 31-39 (2013-03-06)
Rangelia vitalii is a tick-transmitted piroplasm that causes both hemolytic and hemorrhagic disease in dogs in Brazil. The aim of this study was to evaluate the response of the bone marrow in dogs experimentally infected with R vitalii during the
Aboagye Kwarteng Dofuor et al.
Biomolecules, 10(12) (2020-12-17)
In the absence of vaccines, there is a need for alternative sources of effective chemotherapy for African trypanosomiasis (AT). The increasing rate of resistance and toxicity of commercially available antitrypanosomal drugs also necessitates an investigation into the mode of action
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