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About This Item
Empirical Formula (Hill Notation):
C22H34O2
CAS Number:
Molecular Weight:
330.50
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24
Product Name
Eicosapentaenoic acid ethyl ester, European Pharmacopoeia (EP) Reference Standard
SMILES string
O(CC)C(=O)\C=C\C=C\C=C\C=C\C=C\CCCCCCCCC
InChI
1S/C22H34O2/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24-4-2/h12-21H,3-11H2,1-2H3/b13-12+,15-14+,17-16+,19-18+,21-20+
InChI key
DTEMJWLYSQBXEL-MBFZXKRTSA-N
grade
pharmaceutical primary standard
API family
eicosapentaenoic acid
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
shipped in
wet ice
storage temp.
−20°C
Application
Eicosapentaenoic acid ethyl ester EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Satoshi Kajikawa et al.
Prostaglandins, leukotrienes, and essential fatty acids, 80(4), 229-238 (2009-03-31)
Eicosapentaenoic acid (EPA) is a member of the family of n-3 polyunsaturated fatty acids (PUFAs) that are clinically used to treat hypertriglyceridemia. The triglyceride (TG) lowering effect is likely due to an alteration in lipid metabolism in the liver, but
Harold E Bays et al.
The American journal of cardiology, 108(5), 682-690 (2011-06-21)
AMR101 is an omega-3 fatty acid agent containing ≥96% eicosapentaenoic acid ethyl ester and no docosahexaenoic acid. Previous smaller studies suggested that highly purified eicosapentaenoic acid lowered triglyceride (TG) levels without increasing low-density lipoprotein (LDL) cholesterol levels. TG-lowering therapies such
Mariko Morishita et al.
Journal of controlled release : official journal of the Controlled Release Society, 132(2), 99-104 (2008-09-23)
Glucagon-like peptide-1 (GLP-1) is a gut-derived peptide secreted from intestinal L-cells and now considered as an ideal diabetic medicine. Recently, it was reported that the unsaturated fatty acid alpha-linoleic acid promotes the secretion of GLP-1 via a G protein-coupled receptor
Nerea Pérez-Echarri et al.
The British journal of nutrition, 101(7), 1059-1067 (2008-08-30)
Previous studies have demonstrated that the n-3 fatty acid EPA improves insulin resistance induced by high-fat diets. The aim of the present study was to investigate the potential role of visfatin and apelin in the insulin-sensitising effects of EPA ethyl
David Mischoulon et al.
The Journal of clinical psychiatry, 70(12), 1636-1644 (2009-08-28)
To examine the efficacy and tolerability of ethyl-eicosapentaenoate (EPA-E) monotherapy for major depressive disorder (MDD). Fifty-seven adults with DSM-IV MDD were randomly assigned from January 2003 until June 2006 to receive 1 g/d of eicosapentaenoic acid (EPA) or placebo for
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