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E2499900

Etofenamate

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

2-[[3-(Trifluoromethyl)phenyl]amino]benzoic acid 2-(2-hydroxyethoxy)ethyl ester

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About This Item

Empirical Formula (Hill Notation):
C18H18F3NO4
CAS Number:
30544-47-9
Molecular Weight:
369.34
MDL number:
MFCD00242806
UNSPSC Code:
41116107
NACRES:
NA.24

Key Documents

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Product Name

Etofenamate, European Pharmacopoeia (EP) Reference Standard

SMILES string

FC(F)(F)c1cc(ccc1)Nc2c(cccc2)C(=O)OCCOCCO

InChI

1S/C18H18F3NO4/c19-18(20,21)13-4-3-5-14(12-13)22-16-7-2-1-6-15(16)17(24)26-11-10-25-9-8-23/h1-7,12,22-23H,8-11H2

InChI key

XILVEPYQJIOVNB-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

etofenamate

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

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Application

Etofenamate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

hcodes

H301,H410

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

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José Luis Acosta Patiñio et al.
Acta ortopedica mexicana, 21(5), 253-255 (2007-12-28)
To demonstrate that the application of etofenamate is effective in management of acute pain. We conducted a prospective, longitudnal, 6 months trial, which included 22 women and 18 men with intense acute low back pain of mechanical or postural aetiology
Yalcin Golcuk et al.
Clinical toxicology (Philadelphia, Pa.), 48(5), 471-472 (2010-07-01)
Toxic epidermal necrolysis (Lyell syndrome) is a rare, acute, and potentially life-threatening mucocutaneous disease that is most often triggered by drugs. This is the first case of toxic epidermal necrolysis because of treatment with etofenamate of which we are aware.
Uriah Guevara-López et al.
Cirugia y cirujanos, 72(6), 483-490 (2005-02-08)
The analgesic efficacy of intramuscular etofenamate (1 g/day) and intramuscular diclofenac (75 mg/day) was assessed in post-surgical pain relief during a period of 3 days. One hundred ten hospitalized patients undergoing elective surgery were evaluated in an open-label, comparative, randomized
Contact dermatitis from etofenamate.
A Götze et al.
Contact dermatitis, 26(3), 209-209 (1992-03-01)
Allergic and photoallergic contact dermartitis from etofenamate: study of 14 cases.
J J Goday Buján et al.
Contact dermatitis, 61(2), 118-120 (2009-08-27)
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