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E4009

Eosin Y

Name: Eosin Y
Brand: SIAL

Dye content ~99%, Powder

Synonym(s):

2′,4′,5′,7′-Tetrabromofluorescein, Acid Red 87, Bromo acid J. TS, XL, or XX, Bromofluorescein, Bronze Bromo ES, Eosin yellowish, Solvent red 43

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About This Item

Empirical Formula (Hill Notation):

C₂₀H₈Br₄O₅

CAS Number:

15086-94-9

Molecular Weight:

647.89

NACRES:

NA.47

PubChem Substance ID:

24894536

UNSPSC Code:

12171500

EC Number:

239-138-3

MDL number:

MFCD00036189

Colour Index Number:

45380:2

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Product Name

Eosin Y, Dye content ~99 %

form

powder

Quality Level

200

composition

Dye content, ~99%

color

light red to red/pink

solubility

ethanol: 1 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

Oc1c(Br)cc2c(Oc3c(Br)c(O)c(Br)cc3C24OC(=O)c5ccccc45)c1Br

InChI

1S/C20H8Br4O5/c21-11-5-9-17(13(23)15(11)25)28-18-10(6-12(22)16(26)14(18)24)20(9)8-4-2-1-3-7(8)19(27)29-20/h1-6,25-26H

InChI key

DBZJJPROPLPMSN-UHFFFAOYSA-N

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Related Categories

Clinical & Diagnostics

Hematology Stains

Histology Stains

Tissue Diagnostics

Application

Eosin Y has been used as a stain:

to determine the location of the brain sections
for staining of fixed liver tissue
for histological examination of brain sections from the dorsal hippocampus

Biochem/physiol Actions

Eosin Y is a xanthene dye and is used for the differential staining of connective tissue and cytoplasm. In histopathology, it is applied as a counterstain after hematoxylin and before methylene blue. It is also used as a background stain, thereby giving contrast to the nuclear stains.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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epigenetic multiple ligands: mixed histone/protein methyltransferase, acetyltransferase, and class III deacetylase (sirtuin) inhibitors.

Antonello Mai et al.

Journal of medicinal chemistry, 51(7), 2279-2290 (2008-03-20)

A number of new compounds bearing two ortho-bromo- and ortho, ortho-dibromophenol moieties linked through a saturated/unsaturated, linear/(poly)cyclic spacer (compounds 1- 9) were prepared as simplified analogues of AMI-5 (eosin), a recently reported inhibitor of both protein arginine and histone lysine

Synthesis of tetraglucosyl- and tetrapolyamine-tetrabenzoporphyrin conjugates for an application in PDT.

Florian Ménard et al.

Bioorganic & medicinal chemistry, 17(22), 7647-7657 (2009-10-13)

This paper reports the synthesis and characterization of a new class of tetrabenzoporphyrins bearing glucosyl or polyamine units on meso positions to improve the targeting of cancer cells. Photocytotoxic activity of these photosensitizers was tested on cell lines HaCaT and

An immunohistochemical analysis of SERT in the blood-brain barrier of the male rat brain.

Young LW, et al.

Histochemistry and Cell Biology, 144, 321-321 (2015)

Inactivation of NF-kappaB p50 leads to insulin sensitization in liver through post-translational inhibition of p70S6K.

Gao Z, et al.

The Journal of Biological Chemistry, 284, 18368-18368 (2009)

The effects of simvastatin on hippocampal caspase-3 and Bcl-2 expression following kainate-induced seizures in rats.

Sun J, et al.

International Journal of Molecular Medicine, 30, 739-739 (2012)

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Global Trade Item Number

SKU	GTIN
E4009-25G	04061833603482
E4009-5G	04061833603499

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