Key Documents

View All Documentation

F0888

Fura 2-AM

Name: Fura 2-AM
Brand: SIAL

≥95% purity (HPLC), powder

Synonym(s):

Fura-2 pentakis(acetoxymethyl) ester

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₄₄H₄₇N₃O₂₄

CAS Number:

108964-32-5

Molecular Weight:

1001.85

NACRES:

NA.47

PubChem Substance ID:

24894734

UNSPSC Code:

12171500

MDL number:

MFCD00036976

Beilstein/REAXYS Number:

8183748

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Product Name

Fura 2-AM, ≥95% (HPLC)

Quality Level

100

assay

≥95% (HPLC)

form

powder

color

yellow to yellow-green

solubility

acetone: 10 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

SMILES string

CC(=O)OCOC(=O)CN(CC(=O)OCOC(C)=O)c1ccc(C)cc1OCCOc2cc3cc(oc3cc2N(CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O)-c4ncc(o4)C(=O)OCOC(C)=O

InChI

1S/C44H47N3O24/c1-25-7-8-32(46(16-39(53)65-20-60-26(2)48)17-40(54)66-21-61-27(3)49)35(11-25)58-9-10-59-36-12-31-13-37(43-45-15-38(71-43)44(57)69-24-64-30(6)52)70-34(31)14-33(36)47(18-41(55)67-22-62-28(4)50)19-42(56)68-23-63-29(5)51/h7-8,11-15H,9-10,16-24H2,1-6H3

InChI key

VPSRLGDRGCKUTK-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Clinical & Diagnostics

Hematology Stains

Histology Stains

Tissue Diagnostics

General description

Fura 2-AM (Fura 2) is a calcium-specific ratio-metric fluorescent dye. It is also known as acetoxy-methyl-ester. In response to calcium ions, ratio metric dyes like Fura 2 changes their respective excitation or emission spectra. The intracellular calcium concentration is determined by the fluorescence emission ratio or excitation at distinct wavelengths. Fura 2 has an emission peak at 505nm, and the excitation peak ranges between 340-380nm and is the preferred calcium indicator.

Application

Fura 2-AM is a popular probe used to determine dynamic changes in cytosolic free calcium in intact living cells.

Features and Benefits

The major benefits of using the ester form of Fura 2 as Fura 2-AM are: It is cell-permeable. It can be loaded into cells easily. Another advantage of using Fura 2-AM over single wavelength dyes is that the ratio signal is independent of : The dye concentration. Illumination intensity, and Optical path length.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Effects of Taurine or Trehalose supplementation on functional competence of cryopreserved Karan Fries semen.

Chhillar S

Animal Reproduction, 135, 1-1 (2012)

Role of chondroitin 4-sulphate as a receptor for polycation induced human platelet aggregation.

J L Donato et al.

British journal of pharmacology, 119(7), 1447-1453 (1996-12-01)

1. Proteoglycans provide negatively charged sites on the surface of platelets, leukocytes and endothelial cells. Since chondroitin 4-sulphate is the main proteoglycan present on the platelet surface, the role of this molecule in mediating the activation of human platelets by

Assessment of intracellular Ca2+, cAMP and 1,2-diacylglycerol in cryopreserved buffalo (Bubalus bubalis) spermatozoa on supplementation of taurine and trehalose in the extender.

Singh VK

Reproduction in domestic animals = Zuchthygiene, 47, 584-584 (2012)

The human thromboxane A2 receptor alpha isoform (TP alpha) functionally couples to the G proteins Gq and G11 in vivo and is activated by the isoprostane 8-epi prostaglandin F2 alpha.

B T Kinsella et al.

The Journal of pharmacology and experimental therapeutics, 281(2), 957-964 (1997-05-01)

To establish whether the thromboxane A2 (TXA2) receptor (TP) functionally couples to the Gq family of heterotrimeric G proteins in vivo, we have coexpressed the cDNAs coding for the human platelet/placental TP alpha isoform (TP alpha) and the alpha subunits

Assessment of Fura-2 for measurements of cytosolic free calcium.

M W Roe et al.

Cell calcium, 11(2-3), 63-73 (1990-02-01)

Fura-2 has become the most popular fluorescent probe with which to monitor dynamic changes in cytosolic free calcium in intact living cells. In this paper, we describe many of the currently recognized limitations to the use of Fura-2 in living

View All Related Papers

Global Trade Item Number

SKU	GTIN
F0888-1MG	04061833611449
F0888-.5MG	04061832342832

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service