Skip to Content
Merck
CN

F1427

Florfenicol

analytical standard, for drug analysis

Synonym(s):

Aquafen, Nuflor, SCH-25298, [R-(R*,S*)]-2,2-Dichloro-N-[1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C12H14Cl2FNO4S
CAS Number:
73231-34-2
Molecular Weight:
358.21
NACRES:
NA.24
PubChem Substance ID:
329799680
UNSPSC Code:
41116107
MDL number:
MFCD00864834

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Florfenicol, analytical standard, for drug analysis

InChI key

AYIRNRDRBQJXIF-NXEZZACHSA-N

SMILES string

CS(=O)(=O)c1ccc(cc1)[C@@H](O)[C@@H](CF)NC(=O)C(Cl)Cl

InChI

1S/C12H14Cl2FNO4S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-15)16-12(18)11(13)14/h2-5,9-11,17H,6H2,1H3,(H,16,18)/t9-,10-/m1/s1

form

solid

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

Quality Level

100

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

The analytical standard can be used as follows:
  • To measure florfenicol and its main metabolite florfenicol amine in tilapia meat by solid phase extraction (SPE) and ultra high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS)
  • Multi-residue analysis of three amfenicols in animal feed samples by HPLC-MS/MS method, following European Commission Decision 2002/657/EC(2)Determination of florfenicol in different animal feedstuff samples by thin layer chromatography (TLC) coupled with HPLC-UV detection
  • Residue analysis of florfenicol in broiler meat and liver samples by a reversed phase-HPLC method in combination with UV detection at 223 nm
  • Competitive indirect-chemiluminescent enzyme-linked immunosorbent assay (CL-ELISA) based quantitative analysis of florfenicol and its major metabolite florfenicol amine in chicken muscle samples, validated as per Commission Decision 2002/657/EC

General description

Florfenicol is a broad-spectrum amphenicol antibiotic used against diseases affecting domestic and wild animals.

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

signalword

Danger

pictograms

Health hazardEnvironment
GHS08,GHS09

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 1

target_organs

Liver,Brain,Testes,Spinal cord,Blood,gallbladder

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

涉药品监管产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCZ8778
MKCT6679
MKCQ8950
MKCM8996
MKCK6201

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

J R Craig et al.
Journal of animal science, 95(11), 4904-4916 (2018-01-03)
Gilt progeny (GP) are born and weaned lighter than sow progeny (SP) and have higher rates of mortality. This study aimed to quantify the performance and survival differences between GP and SP throughout the entire production cycle from birth to
Shih-Wei Wu et al.
Toxins, 12(10) (2020-10-08)
A two-analyte immunochromatographic strip (immunostrip) was developed for the simultaneous detection of aflatoxin M1 (AFM1) and chloramphenicol (CAP) in milk. Protein conjugates (AFM1-ovalbumin (OVA) and CAP-OVA) and goat anti-rabbit IgG were respectively drawn on nitrocellulose membrane as two test lines
Chun-Liu Dong et al.
Frontiers in pharmacology, 8, 553-553 (2017-09-07)
Invasive infections due to
Ye Duan et al.
Applied biochemistry and biotechnology, 180(8), 1644-1656 (2016-09-11)
Chloramphenicol (CAP) has been widely used to treat bacterial infections in livestock and aquatic animals. To reduce the risk of CAP residues, an efficient technology to rapidly detect CAP residues in animal-sourced food is expressly needed. In this study, magnetic
Joren De Smet et al.
Frontiers in pharmacology, 9, 1265-1265 (2018-11-22)
Florfenicol, which is licensed for veterinary use only, proves to be a potent antimicrobial for treatment of respiratory disease. However, the subsequent exposure of the gut microbiota to florfenicol is not well described. Hence, the effect of various administration protocols
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service