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F6145

Fenspiride hydrochloride

analytical standard, for drug analysis

Synonym(s):

8-(2-Phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C15H20N2O2 · HCl
CAS Number:
5053-08-7
Molecular Weight:
296.79
UNSPSC Code:
41116107
PubChem Substance ID:
329799751
EC Number:
225-752-9
MDL number:
MFCD00133315
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grade

analytical standard

Quality Segment

200

assay

>99% (TLC)

form

powder

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

color

white

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

Cl.O=C1NCC2(CCN(CCc3ccccc3)CC2)O1

InChI

1S/C15H20N2O2.ClH/c18-14-16-12-15(19-14)7-10-17(11-8-15)9-6-13-4-2-1-3-5-13;/h1-5H,6-12H2,(H,16,18);1H

InChI key

FIKFLLIUPUVONI-UHFFFAOYSA-N

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152), HRH1(3269)

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Bronchodilator with anti-inflammatory properties. Inhibits mucus secretion and reduces the release of tachykinins at a prejunctional level by its anti-muscarinic action. It also may be an antagonist at α adrenergic and H1 histamine receptors.
Fenspiride hydrochloride possesses anti-allergic and anti-bronchoconstrictive properties. It is used as a drug to treat inflammatory conditions of the upper and lower respiratory tracts. Experimental studies state that fenspiride has an ability to reduce the development of myringosclerosis, possibly by restricting the formation of oxygen-derived free radicals.
Bronchodilator with anti-inflammatory properties. Inhibits mucus secretion and reduces the release of tachykinins at a prejunctional level by its anti-muscarinic action. It also may be an antagonist at α adrenergic and H1 histamine receptors.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

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