F8639
Famprofazone
analytical standard
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About This Item
Empirical Formula (Hill Notation):
C24H31N3O
CAS Number:
Molecular Weight:
377.52
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
245-284-9
MDL number:
grade
analytical standard
Quality Segment
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
SMILES string
CC(C)C1=C(CN(C)C(C)Cc2ccccc2)N(C)N(c3ccccc3)C1=O
InChI
1S/C24H31N3O/c1-18(2)23-22(17-25(4)19(3)16-20-12-8-6-9-13-20)26(5)27(24(23)28)21-14-10-7-11-15-21/h6-15,18-19H,16-17H2,1-5H3
InChI key
GNUXVOXXWGNPIV-UHFFFAOYSA-N
General description
Famprofazone is a pyrazole derivative and belongs to the class of non-steroidal anti-inflammatory drugs. It is widely used as an analgesic and antipyretic in medical applications.
Application
Famprofazone may be used as an analytical reference standard for the quantification of the analyte in biological samples using liquid chromatography coupled to tandem mass spectrometry.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
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J T Cody
Forensic science international, 80(3), 189-199 (1996-07-12)
Fourteen different metabolic precursors of amphetamine or methamphetamine have previously been identified. Many of these drugs are available only by prescription and several are only available in some parts of the world and not in others. One of these drugs
F Musshoff
Drug metabolism reviews, 32(1), 15-44 (2000-03-11)
The interpretation of methamphetamine and amphetamine positive test results in biological samples is a challenge to clinical and forensic toxicology for several reasons. The effects of pH and dilution of urine samples and the knowledge about legitimate and illicit sources
E S Oh et al.
Xenobiotica; the fate of foreign compounds in biological systems, 22(3), 377-384 (1992-03-01)
1. To obtain further evidence for the metabolic formation of methamphetamine from famprofazone in man, concentrations of methamphetamine in plasma, as well as in urine, were measured by g.l.c. In addition, intact famprofazone and famprofazone N-oxide were analysed in the