F8639
Famprofazone
analytical standard
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About This Item
Empirical Formula (Hill Notation):
C24H31N3O
CAS Number:
Molecular Weight:
377.52
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
245-284-9
MDL number:
Product Name
Famprofazone, analytical standard
InChI key
GNUXVOXXWGNPIV-UHFFFAOYSA-N
InChI
1S/C24H31N3O/c1-18(2)23-22(17-25(4)19(3)16-20-12-8-6-9-13-20)26(5)27(24(23)28)21-14-10-7-11-15-21/h6-15,18-19H,16-17H2,1-5H3
SMILES string
CC(C)C1=C(CN(C)C(C)Cc2ccccc2)N(C)N(c3ccccc3)C1=O
grade
analytical standard
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
Quality Level
Application
Famprofazone may be used as an analytical reference standard for the quantification of the analyte in biological samples using liquid chromatography coupled to tandem mass spectrometry.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
General description
Famprofazone is a pyrazole derivative and belongs to the class of non-steroidal anti-inflammatory drugs. It is widely used as an analgesic and antipyretic in medical applications.
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J T Cody
Forensic science international, 80(3), 189-199 (1996-07-12)
Fourteen different metabolic precursors of amphetamine or methamphetamine have previously been identified. Many of these drugs are available only by prescription and several are only available in some parts of the world and not in others. One of these drugs
E S Oh et al.
Xenobiotica; the fate of foreign compounds in biological systems, 22(3), 377-384 (1992-03-01)
1. To obtain further evidence for the metabolic formation of methamphetamine from famprofazone in man, concentrations of methamphetamine in plasma, as well as in urine, were measured by g.l.c. In addition, intact famprofazone and famprofazone N-oxide were analysed in the
F Musshoff
Drug metabolism reviews, 32(1), 15-44 (2000-03-11)
The interpretation of methamphetamine and amphetamine positive test results in biological samples is a challenge to clinical and forensic toxicology for several reasons. The effects of pH and dilution of urine samples and the knowledge about legitimate and illicit sources
Identification of new urinary metabolites of famprofazone in humans
Journal of Analytical Toxicology, 22(1), 55-60 (1998)
Elisangela de Souza Santos et al.
Talanta, 191, 545-552 (2018-09-29)
Forensic toxicologists typically work with body fluids, such as blood and urine, or visceral tissues. The analysis of alternative samples, such as bone marrow, can be requested when the commonly used samples are unavailable due to an extended time lapse
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
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