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Merck
CN

H8000

L-Histidine

≥99% (TLC), ReagentPlus®

Synonym(s):

(S)-2-Amino-3-(4-imidazolyl)propionic acid, NSC 137773

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About This Item

Empirical Formula (Hill Notation):
C6H9N3O2
CAS Number:
71-00-1
Molecular Weight:
155.15
PubChem Substance ID:
24895816
eCl@ss:
32160406
UNSPSC Code:
12352209
NACRES:
NA.26
EC Number:
200-745-3
MDL number:
MFCD00064315
Beilstein/REAXYS Number:
84088

Key Documents

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Product Name

L-Histidine, ReagentPlus®, ≥99% (TLC)

InChI

1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1

SMILES string

N[C@@H](Cc1c[nH]cn1)C(O)=O

InChI key

HNDVDQJCIGZPNO-YFKPBYRVSA-N

product line

ReagentPlus®

assay

≥99% (TLC)

form

powder

color

white to off-white

mp

282 °C (dec.) (lit.)

solubility

0.5 M HCl: 50 mg/mL

application(s)

cell analysis

Quality Level

200

Gene Information

human ... CA1(759), CA2(760)

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Application

L-histidine has been used for the selection of transformed cells. It has also been used to study its effects on the formation of verteporfin cross-linked oligomers in cellular homogenates.

Biochem/physiol Actions

L-Histidine is an essential amino acid. It binds to metal ions and may aid in the transport of copper. Histidine is widely present at the active sites of enzymes. It also has a role in binding of heme groups, macromolecules and phosphate groups in the binding sites of proteins.
Precursor of histamine by action of histidine decarboxylase.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000522147
0000522148
0000522146
0000522149
0000522146

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Verteporfin-induced formation of protein cross-linked oligomers and high molecular weight complexes is mediated by light and leads to cell toxicity
Eleni K
Scientific Reports (2017)
Roger L. Lundblad
Chemical Reagents for Protein Modification (2014)
Catherine Collin, Masaru Minami, Hasan Parvez, Hideya Saito, Simone Parvez, Qureshi, Claude Reiss
Advances in Neurochemistry (2005)
Kakulavarapu V Rama Rao et al.
The American journal of pathology, 176(3), 1400-1408 (2010-01-16)
Brain edema and the associated increase in intracranial pressure are potentially lethal complications of acute liver failure (ALF). Astrocyte swelling (cytotoxic edema) represents a significant component of the brain edema in ALF, and elevated blood and brain ammonia levels have
Markerless Gene Editing in the Hyperthermophilic Archaeon Thermococcus kodakarensis
Alexandra m
Bio-protocol (2017)
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