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H9645

p-Hydroxymethamphetamine

Name: <I>p</I>-Hydroxymethamphetamine
Brand: SIAL

analytical standard, for drug analysis

Synonym(s):

Pholderin

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About This Item

Empirical Formula (Hill Notation):

C₁₀H₁₅NO

CAS Number:

370-14-9

Molecular Weight:

165.23

NACRES:

NA.24

PubChem Substance ID:

329815268

UNSPSC Code:

41116107

EC Number:

206-725-0

MDL number:

MFCD00178702

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Properties

Quality Level

200

assay

≥98% (TLC)

drug control

Home Office Schedule 1; regulated under CDSA - not available from Sigma-Aldrich Canada

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

storage temp.

−20°C

SMILES string

CNC(C)Cc1ccc(O)cc1

InChI

1S/C10H15NO/c1-8(11-2)7-9-3-5-10(12)6-4-9/h3-6,8,11-12H,7H2,1-2H3

InChI key

SBUQZKJEOOQSBV-UHFFFAOYSA-N

Description

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

A metabolite of methamphetamine; sympathomimetic

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number

0000415093

0000148527

0000130469

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Simultaneous determination of methamphetamine and its metabolites in monkey urine by gas chromatography/mass spectrometry with selected ion monitoring.

T Yamamoto et al.

Journal of analytical toxicology, 13(2), 117-119 (1989-03-01)

A sensitive and specific gas chromatography/mass spectrometry (GC/MS) method has been developed for the simultaneous analysis of methampthetamine and its metabolites (amphetamine, p-hydroxymethamphetamine, and p-hydroxyamphetamine) in monkey urine. The method has been applied to the analysis of urine samples from

Shimosato, K., et al.

Journal of Chromatographic Science, 377, 279-279 (1986)

Direct determination of glucuronide and sulfate of p-hydroxymethamphetamine in methamphetamine users' urine.

Noriaki Shima et al.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 830(1), 64-70 (2005-11-03)

Two conjugates of p-hydroxymethamphetamine (p-OHMA), p-OHMA-glucuronide (p-OHMA-Glu) and p-OHMA-sulfate (p-OHMA-Sul) have been identified in methamphetamine (MA) users' urine by using liquid chromatography-high resolution tandem mass spectrometry (LC-HRMS-MS). The synthesis of p-OHMA-Glu and p-OHMA-Sul, and an LC-MS procedure for the simultaneous

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Global Trade Item Number

SKU	GTIN
H9645-25MG	04061833284971