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I8377

Iodonitrotetrazolium chloride

Name: Iodonitrotetrazolium chloride
Brand: SIAL

Used in colorimetric assays.

Synonym(s):

2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyl-2H-tetrazolium chloride, p-Iodonitrotetrazolium Violet, INT

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About This Item

Empirical Formula (Hill Notation):

C₁₉H₁₃ClIN₅O₂

CAS Number:

146-68-9

Molecular Weight:

505.70

UNSPSC Code:

12171500

NACRES:

NA.47

PubChem Substance ID:

24896138

EC Number:

205-676-2

Beilstein/REAXYS Number:

4093224

MDL number:

MFCD00011961

Assay:

≥98% (TLC)

Form:

powder

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Properties

Quality Level

200

assay

≥98% (TLC)

form

powder

mp

240 °C (dec.) (lit.)

solubility

H₂O: 4 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

2-8°C

SMILES string

[Cl-].[O-][N+](=O)c1ccc(cc1)-[n+]2nc(nn2-c3ccc(I)cc3)-c4ccccc4

InChI

1S/C19H13IN5O2.ClH/c20-15-6-8-16(9-7-15)23-21-19(14-4-2-1-3-5-14)22-24(23)17-10-12-18(13-11-17)25(26)27;/h1-13H;1H/q+1;/p-1

InChI key

JORABGDXCIBAFL-UHFFFAOYSA-M

Description

Application

Iodonitrotetrazolium chloride has been used for the staining of cells. It has been used as a coupling agent in the enzymatic assay of D-arabinitol.

Electron acceptor for the colorimetric assay of various dehydrogenases

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pictograms

GHS02,GHS07

signalword

Danger

hcodes

H228,H335

pcodes

P210 - P240 - P241 - P261 - P271 - P280

Hazard Classifications

Flam. Sol. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

4.1B - Flammable solid hazardous materials

wgk

WGK 3

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Certificates of Analysis (COA)

Lot/Batch Number

0000507090

0000488396

0000464388

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Constitutive activation of pp125fak in newly isolated human breast cancer cell lines.

Ignatoski KMW and Ethier SP

Breast Cancer Research and Treatment, 54, 173-173 (1999)

Use of slow filtration columns to assess oxygen respiration, consumption of dissolved organic carbon, nitrogen transformations, and microbial parameters in hyporheic sediments.

F Mermillod-Blondin et al.

Water research, 39(9), 1687-1698 (2005-05-19)

Biogeochemical processes mediated by microorganisms in river sediments (hyporheic sediments) play a key role in river metabolism. Because biogeochemical reactions in the hyporheic zone are often limited to the top few decimetres of sediments below the water-sediment interface, slow filtration

Inhibition of the neutrophil NADPH oxidase and associated H+ channel by diethyl pyrocarbonate (DEPC), a histidine-modifying agent: evidence for at least two target sites.

T J Mankelow et al.

The Biochemical journal, 358(Pt 2), 315-324 (2001-08-22)

Diethyl pyrocarbonate (DEPC), a histidine-modifying reagent, has been utilized to demonstrate the importance of histidine residues in the functioning of proteins. In previous studies of the NADPH oxidase, histidine residues have been determined to be important in the ability of

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Global Trade Item Number

SKU	GTIN
I8377-5G	04061835347803
I8377-1G	04061835347797
I8377-25G	04061833858561
I8377-250MG	04061833858554