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L4158

Sigma-Aldrich

Lithium acetate dihydrate

BioXtra

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Synonym(s):
Acetic acid lithium salt
Linear Formula:
CH3COOLi · 2H2O
CAS Number:
6108-17-4
Molecular Weight:
102.02
Beilstein:
3564320
EC Number:
208-914-3
MDL number:
MFCD00066949
PubChem Substance ID:
24896363
NACRES:
NA.31

product line

BioXtra

Quality Level

200

form

solid

impurities

≤0.001% Phosphorus (P)
≤0.1% Insoluble matter

mp

53-56 °C (lit.)

solubility

H2O: 1 M, clear, colorless

anion traces

chloride (Cl-): ≤0.5%
sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.0005%
Ca: ≤0.005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.001%
NH4+: ≤0.05%
Na: ≤0.005%
Pb: ≤0.001%
Zn: ≤0.0005%

SMILES string

[Li+].[H]O[H].[H]O[H].CC([O-])=O

InChI

1S/C2H4O2.Li.2H2O/c1-2(3)4;;;/h1H3,(H,3,4);;2*1H2/q;+1;;/p-1

InChI key

IAQLJCYTGRMXMA-UHFFFAOYSA-M

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General description

Lithium acetate dihydrate is one of the commercially available forms of lithium acetate. Lithium acetate is a common salt with variety of applications such as, product for efficient yeast transformation, drug formulation and therapy, lithium-6 CP/MAS standard, solvent and catalyst. In addition, it is also used as a buffer for gel electrophoresis of DNA and RNA, additive or catalyst for textiles and polymer production and as a precursor material for batteries and ferromagnetic nanoparticles.

Application

Lithium acetate dihydrate has been used for yeast transformation.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Single-step marker switching in Schizosaccharomyces pombe using a lithium acetate transformation protocol
Brown SD and Lorenz A
Bio-protocol, 6(24), 295-316 (2016)
MtNODULE ROOT1 and MtNODULE ROOT2 are essential for indeterminate nodule identity
Magne K, et al.
Plant Physiology, 178(1), 295-316 (2018)
Anhydrous lithium acetate polymorphs and its hydrates: three-dimensional coordination polymers
Martinez Casado FJ, et al.
Crystal Growth & Design, 11(4), 1021-1032 (2011)
Mating based split-ubiquitin assay for detection of protein interactions
Horaruang W and Zhang B
Bio-protocol, 7(4), e2258-e2258 (2017)
Mireia Garriga-Canut et al.
Methods (San Diego, Calif.), 178, 19-32 (2019-09-08)
Understanding which proteins and RNAs directly interact is crucial for revealing cellular mechanisms of gene regulation. Efficient methods allowing to detect RNA-protein interactions and dissect the underlying molecular origin for RNA-binding protein (RBP) specificity are in high demand. The recently
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Articles

Introduction to Yeast Transformation

Transformation is the process by which exogenous DNA is introduced into a cell, resulting in a heritable change or genetic modification. This was first reported in Streptococcus pneumoniae by Griffith in 1928. Transforming principle of DNA was demonstrated by Avery et al. in 1944.

Protocols

Yeast Transformation Protocols

Yeasts are considered model systems for eukaryotic studies as they exhibit fast growth and have dispersed cells.

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