O5380
Oxethazaine
analytical standard
Synonym(s):
2-Hydroxyethyliminobis(N-[α,α-dimethylphenethyl]-N-methylacetamide), Oxetacaine
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About This Item
Empirical Formula (Hill Notation):
C28H41N3O3
CAS Number:
Molecular Weight:
467.64
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
204-780-5
MDL number:
grade
analytical standard
Quality Level
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
SMILES string
CN(C(=O)CN(CCO)CC(=O)N(C)C(C)(C)Cc1ccccc1)C(C)(C)Cc2ccccc2
InChI
1S/C28H41N3O3/c1-27(2,19-23-13-9-7-10-14-23)29(5)25(33)21-31(17-18-32)22-26(34)30(6)28(3,4)20-24-15-11-8-12-16-24/h7-16,32H,17-22H2,1-6H3
InChI key
FTLDJPRFCGDUFH-UHFFFAOYSA-N
General description
Oxethazaine is a topical anesthetic, administered as an antacid for treating pain associated with duodenal ulcer, esophagitis and gastritis.
Application
Oxethazaine may be used as an analytical reference standard for the quantification of the analyte in biological samples using liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
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A Pap et al.
Acta medica Academiae Scientiarum Hungaricae, 37(3), 305-313 (1980-01-01)
The effect of submaximal doses of intravenous atropine and their combination with topical anaesthesia of the intestine by oxethazaine-HCl was investigated in conscious rats. I. Basal water, bicarbonate and protein secretion were significantly augmented after diversion of pancreatic juice. On
The abuse potential of oxethazaine: effects of oxethazaine on drug-seeking behavior and analysis of its metabolites in plasma and hair in animal models
Lee Y-S, et al.
Pharmacology, Biochemistry, and Behavior, 105(3), 98-104 (2013)
A Zanni et al.
Current medical research and opinion, 10(2), 128-134 (1986-01-01)
A double-blind study was carried out in 40 patients with typical ulcer pain and suffering from gastric or duodenal ulcer to compare the pain-relieving efficacy of oxethazaine/magnesium and aluminium hydroxide mixture with that of the antacid combination alone. Patients took
Global Trade Item Number
| SKU | GTIN |
|---|---|
| O5380-5G | 04061833652893 |