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P1037

Sigma-Aldrich

Phenol

for molecular biology

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Synonym(s):
Hydroxybenzene
Linear Formula:
C6H5OH
CAS Number:
108-95-2
Molecular Weight:
94.11
Beilstein:
969616
EC Number:
203-632-7
MDL number:
MFCD00002143
PubChem Substance ID:
24898145
NACRES:
NA.31

grade

for molecular biology

Quality Level

100

vapor density

3.24 (vs air)

vapor pressure

0.09 psi ( 55 °C)
0.36 mmHg ( 20 °C)

Assay

≥99.0% (GC)

form

crystals

autoignition temp.

1319 °F

does not contain

preservative

expl. lim.

8.6 %

impurities

≤2 ppm Mg
≤5 ppm Pb

color

white to off-white

bp

182 °C (lit.)

mp

40-42 °C (lit.)

density

1.071 g/mL at 25 °C (lit.)

suitability

suitable for molecular biology

storage temp.

2-8°C

SMILES string

Oc1ccccc1

InChI

1S/C6H6O/c7-6-4-2-1-3-5-6/h1-5,7H

InChI key

ISWSIDIOOBJBQZ-UHFFFAOYSA-N

Gene Information

human ... GABRA1(2554)

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Application

Phenol has been used:
  • in solid-phase peptide synthesis
  • as a component of DNA extraction buffer
  • as a component of Alexander′s stain solution

Biochem/physiol Actions

Phenol is majorly used in cosmetics and pharmaceuticals. Phenol pollutes water bodies and inhibits the γ-aminobutyric acid receptor (GABAAR)-coupled chloride ATPase function in the fish brain.

Packaging

Redistilled and packaged under nitrogen in amber bottles.

related product

Product No.
Description
Pricing

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Muta. 2 - Skin Corr. 1B - STOT RE 2

Storage Class Code

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 2

Flash Point(F)

177.8 °F - closed cup

Flash Point(C)

81 °C - closed cup

Regulatory Information

危险化学品

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Effect of phenol on the GABAAR-coupled Cl-/HCO3-ATPase from fish brain: An in vitro approach on the enzyme function
Menzikov SA
Toxicology in vitro, 46(1), 129-136 (2018)
Single prokaryotic cell isolation and total transcript amplification protocol for transcriptomic analysis.
Kang Y, et al.
Nature Protocols, 10(7), 974-974 (2015)
Rapid separation of Arabidopsis male gametophyte developmental stages using a Percoll gradient
Duplakova N, et al.
Nature Protocols, 11(10), 1817-1817 (2016)
Comparative QSAR evidence for a free-radical mechanism of phenol-induced toxicity
Hansch C, et al.
Chemico-Biological Interactions, 127(1), 61-72 (2000)
Zhibo Liu et al.
Nature protocols, 10(9), 1423-1432 (2015-08-28)
Herein we present a general protocol for the functionalization of biomolecules with an organotrifluoroborate moiety so that they can be radiolabeled with aqueous (18)F fluoride ((18)F(-)) and used for positron emission tomography (PET) imaging. Among the β(+)-emitting radionuclides, fluorine-18 ((18)F)
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