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P1254

Sigma-Aldrich

Brij® L23

suitable for Stein-Moore chromatography

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Synonym(s):
Brij 35, C12E23, Polyoxyethylene (23) lauryl ether
CAS Number:
9002-92-0
MDL number:
MFCD00080891
PubChem Substance ID:
24898176
NACRES:
NA.21

description

non-ionic

Quality Level

200

form

solid

mol wt

micellar avg mol wt 48,000
estimated mol wt 1198

aggregation number

20-40

CMC

91 μM

transition temp

cloud point >100 °C

HLB

16.9

suitability

suitable for Stein-Moore chromatography

SMILES string

CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

InChI

1S/C58H118O24/c1-2-3-4-5-6-7-8-9-10-11-13-60-15-17-62-19-21-64-23-25-66-27-29-68-31-33-70-35-37-72-39-41-74-43-45-76-47-49-78-51-53-80-55-57-82-58-56-81-54-52-79-50-48-77-46-44-75-42-40-73-38-36-71-34-32-69-30-28-67-26-24-65-22-20-63-18-16-61-14-12-59/h59H,2-58H2,1H3

InChI key

IEQAICDLOKRSRL-UHFFFAOYSA-N

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Related Categories

Application

Non-ionic detergent. Useful for the extraction of membrane proteins. Typically used in the range of 0.1-1%.

Legal Information

Brij is a registered trademark of Croda International PLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

300.2 °F - open cup

Flash Point(C)

> 149 °C - open cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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T Tobimatsu et al.
Archives of biochemistry and biophysics, 347(1), 132-140 (1997-11-05)
Recombinant adenosylcobalamin-dependent diol dehydratase of Klebsiella oxytoca overexpressed in Escherichia coli was purified to homogeneity. The enzyme has a low solubility and was extracted from the crude membrane fraction with 1% Brij 35 in a high recovery. Subsequent chromatography on
K Yamamoto et al.
Biochimica et biophysica acta, 790(3), 208-218 (1984-11-09)
Two forms of an acid proteinase have been purified from human erythrocyte membranes by a simple method involving selective extraction with 0.5% Brij 35, affinity chromatography on pepstatin A-Sepharose 4B, and chromatography on Sephacryl S-200 and DEAE-Sephadex G-100. One species
Darío Morais et al.
Rhinology, 50(1), 80-86 (2012-04-04)
Hereditary Haemorrhagic Telangiectasia or Rendu-Osler-Weber syndrome is a rare autosomal dominant vascular disease characterized by mucocutaneous and gastrointestinal telangiectases and localized arteriovenous malformations in lung, brain and liver. Epistaxis, due to rupture of telangiectases of the nasal mucosa, is the
N Shadid et al.
The British journal of surgery, 99(8), 1062-1070 (2012-05-26)
New minimally invasive treatment modalities, such as ultrasound-guided foam sclerotherapy (UGFS), are becoming more popular. In a multicentre randomized controlled non-inferiority trial, the effectiveness and costs of UGFS and surgery for treatment of the incompetent great saphenous vein (GSV) were
Otte Brosjö et al.
Acta orthopaedica, 84(5), 502-505 (2013-11-01)
Recent data suggest that percutaneous sclerotherapy is a safe alternative to surgery for treatment of aneurysmal bone cysts (ABCs). We present our experience of this method. We retrospectively analyzed data from 38 consecutive patients treated with repeated injections of polidocanol.
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