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Merck
CN

P2100000

Piperazine hydrate

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Piperazine hexahydrate

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About This Item

Empirical Formula (Hill Notation):
C4H10N2 · 6H2O
CAS Number:
Molecular Weight:
194.23
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
4455527
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Product Name

Piperazine hydrate, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C4H10N2.6H2O/c1-2-6-4-3-5-1;;;;;;/h5-6H,1-4H2;6*1H2

SMILES string

[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].C1CNCCN1

InChI key

AVRVZRUEXIEGMP-UHFFFAOYSA-N

grade

pharmaceutical primary standard

vapor pressure

0.8 mmHg ( 20 °C)

API family

piperazine

manufacturer/tradename

EDQM

bp

145-156 °C (lit.)

mp

42-44 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Application

Piperazine hydrate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

pictograms

Health hazardCorrosion

signalword

Danger

Hazard Classifications

Repr. 2 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 1

flash_point_f

190.4 °F - closed cup

flash_point_c

88 °C - closed cup

Regulatory Information

危险化学品
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Christopher D Smith et al.
Clinical medicine (London, England), 14(4), 409-415 (2014-08-08)
The use of novel psychoactive substances ('legal highs' or 'designer drugs') is increasing worldwide. Patients misusing such substances have been reported to experience severe or prolonged side effects requiring admission to acute or critical care wards. These complications can be
Rajangam Vinodh et al.
Journal of nanoscience and nanotechnology, 14(6), 4639-4648 (2014-04-18)
Chloro-functionalized mesoporous MCM-41, SBA-15, MCM-48 and KIT-6 were synthesized by co-condensation of 3-chloropropyl-trimethoxy-silane (CPTMS) and rice husk ash sodium silicate solution, which is subsequently grafted with a heterocyclic amine, homopiperazine (HPZ). X-ray powder diffraction and BET analysis of the chloro-functionalized

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