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Merck
CN

P2125

D-Pantethine

analytical standard

Synonym(s):

Bis(N-pantothenylamidoethyl) disulfide, LBF factor, Pantethein oxidized form

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About This Item

Empirical Formula (Hill Notation):
C22H42N4O8S2
CAS Number:
Molecular Weight:
554.72
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
240-842-8
MDL number:
Technical Service
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biological source

synthetic (organic)

Quality Level

grade

analytical standard

assay

≥90%

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

color

white

application(s)

forensics and toxicology
veterinary
vitamins, nutraceuticals, and natural products

format

neat

storage temp.

2-8°C

SMILES string

CC(C)(CO)[C@@H](O)C(=O)NCCC(=O)NCCSSCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)CO

InChI

1S/C22H42N4O8S2/c1-21(2,13-27)17(31)19(33)25-7-5-15(29)23-9-11-35-36-12-10-24-16(30)6-8-26-20(34)18(32)22(3,4)14-28/h17-18,27-28,31-32H,5-14H2,1-4H3,(H,23,29)(H,24,30)(H,25,33)(H,26,34)/t17-,18-/m0/s1

InChI key

DJWYOLJPSHDSAL-ROUUACIJSA-N

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.


Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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G Friberg et al.
Current eye research, 15(12), 1182-1190 (1996-12-01)
Solutions of the bovine lens protein gamma B (or gamma II) crystallin at neutral pH in the absence of reducing agents, undergo a slow, partial conversion to a new protein species, gamma IIH. This species is an aggregate composed of
D H Fisher et al.
Journal of pharmaceutical and biomedical analysis, 15(5), 653-662 (1997-02-01)
In several animal models, preliminary studies have indicated that pantethine may inhibit cataract formation. Therefore, preclinical trials need to be conducted to study the pharmacology of pantethine in the ocular lens and to establish its efficacy. Since pantethine, which is
J I Clark et al.
Proceedings of the National Academy of Sciences of the United States of America, 93(26), 15185-15189 (1996-12-24)
The effects of pantethine, glutathione, and selected chemical reagents on the anti-aggregation activity of alpha-crystallin was evaluated. Protein aggregation was monitored by light scattering of solutions of denatured beta L-crystallin or alcohol dehydrogenase (ADH). The ratios of beta L-crystallin/alpha-crystallin and



Global Trade Item Number

SKUGTIN
P2125-5G04061833428665
P2125-1G04061826692219