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Merck
CN

P3015

Sigma-Aldrich

Poly(ethylene glycol)

greener alternative

average mol wt 200

Synonym(s):

Polyethylene glycol, PEG

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About This Item

Linear Formula:
H(OCH2CH2)nOH
CAS Number:
25322-68-3
MDL number:
MFCD00081839
UNSPSC Code:
12352104
PubChem Substance ID:
24898381
NACRES:
NA.21

Key Documents

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form

liquid

Quality Level

200

mol wt

average mol wt 200

greener alternative product characteristics

Safer Solvents and Auxiliaries
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pH

4.5-7.5

viscosity

4.3 cSt(210 °F)(lit.)

mp

-65 °C (lit.)

greener alternative category

Aligned

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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General description

Poly (ethylene glycol) (PEG) is non-ionic, hydrophilic and non-toxic polymer. It is widely used in the emerging field of polymer‐based drug delivery. PEG is available in different molecular weights. It facilitates the purification and crystal growth of proteins and nucleic acids. PEG and dextran together result in aqueous polymer two phase system, which is required for the purification of biological materials. It also interacts with cell membrane, thereby allowing cell fusion.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.

Application

Poly(ethylene glycol) has been used in the preparation of methyl cellulose (MC)-based polymer electrolytes. It has also been used as a solvent to analyse the molecular weight cut off and rejection studies of nanofiltration membranes.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000458152
0000458151
0000458151
0000458152
MKCX6430

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Poly(Ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications (2013)
Electrical double-layer capacitors with plasticized polymer electrolyte based on methyl cellulose
Shuhaimi NEA, et al.
Polymer Bull., 69(7), 807-826 (2012)
Characteristics of nanofiltration membranes in aqueous ethanol
Tsui EM and Cheryan M
Journal of Membrane Science , 237(1-2), 61-69 (2004)
Yi-Zhong Gu et al.
Toxicological sciences : an official journal of the Society of Toxicology (2019-08-14)
MK-7680, a cyclic nucleotide prodrug, caused significant kidney tubule injury in female rats when administered orally at 1000 mg/kg/day for 2 weeks using 10% Polysorbate 80 as vehicle. However, kidney injury was absent when MK-7680 was administered at the same dose
Poly (ethylene glycol) in drug delivery: pros and cons as well as potential alternatives.
Knop K, et al.
Angewandte Chemie (International Edition in English), 49(36), 6288-6308 (2010)
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